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- W2212038364 abstract "To the Editor: We have read with great interest the randomized clinical trial (RCT) by Shenouda et al ( 1 Shenouda G. Zhang Q. Ang K.K. et al. Long-term results of Radiation Therapy Oncology Group 9903: A randomized phase 3 trial to assess the effect of erythropoietin on local-regional control in anemic patients treated with radiation therapy for squamous cell carcinoma of the head and neck. Int J Radiat Oncol Biol Phys. 2015; 91: 907-915 Abstract Full Text Full Text PDF PubMed Scopus (17) Google Scholar ) assessing whether the addition of erythropoietin (EPO) would improve the outcomes of radiation therapy (RT) in patients with mild-to-moderate anemia during treatment for head and neck carcinoma (HNC). The results did not show a benefit for patients receiving EPO. The findings were in concordance with the adverse effects described in a previous meta-analysis of similar RCTs ( 2 Bohlius J. Schmidlin K. Brillant C. et al. Recombinant human erythropoiesis-stimulating agents and mortality in patients with cancer: A meta-analysis of randomised trials. Lancet. 2009; 373: 1532-1542 Abstract Full Text Full Text PDF PubMed Scopus (499) Google Scholar ). Long-Term Results of Radiation Therapy Oncology Group 9903: A Randomized Phase 3 Trial to Assess the Effect of Erythropoietin on Local-Regional Control in Anemic Patients Treated With Radiation Therapy for Squamous Cell Carcinoma of the Head and NeckInternational Journal of Radiation Oncology, Biology, PhysicsVol. 91Issue 5PreviewThis paper reports long-term results of RTOG 9903, to determine whether the addition of erythropoietin (EPO) would improve the outcomes of radiation therapy (RT) in mildly to moderately anemic patients with head and neck squamous cell carcinoma (HNSCCa). Full-Text PDF" @default.
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- W2212038364 date "2015-11-01" @default.
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- W2212038364 title "In Regard to Shenouda et al" @default.
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- W2212038364 doi "https://doi.org/10.1016/j.ijrobp.2015.06.036" @default.
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