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• W2212093853 endingPage "2018" @default.
• W2212093853 startingPage "2013" @default.
• W2212093853 abstract "In skeletal muscle, phosphocreatine (PCr) recovery from submaximal exercise has become a reliable and accepted measure of muscle oxidative capacity. During exercise, O 2 availability plays a role in determining maximal oxidative metabolism, but the relationship between O 2 availability and oxidative metabolism measured by 31 P-magnetic resonance spectroscopy (MRS) during recovery from exercise has never been studied. We used 31 P-MRS to study exercising human gastrocnemius muscle under conditions of varied fractions of inspired O 2 [Formula: see text]) to test the hypothesis that varied O 2 availability modulates PCr recovery from submaximal exercise. Six male subjects performed three bouts of 5-min steady-state submaximal plantar flexion exercise followed by 5 min of recovery in a 1.5-T magnet while breathing three different[Formula: see text] concentrations (0.10, 0.21, and 1.00). Under each[Formula: see text] treatment, the PCr recovery time constants were significantly different, being longer in hypoxia [33.5 ± 4.1 s (SE)] and shorter in hyperoxia (20.0 ± 1.8 s) than in normoxia (25.0 ± 2.7 s) ( P ≤ 0.05). End-exercise pH was not significantly different among the three treatments (7.08 ± 0.01 for 0.10, 7.04 ± 0.01 for 0.21, and 7.04 ± 0.02 for 1.00). These results demonstrate that PCr recovery is significantly altered by[Formula: see text] and suggest that, after submaximal exercise, PCr recovery, under normoxic conditions, is limited by O 2 availability." @default.
• W2212093853 created "2016-06-24" @default.
• W2212093853 creator A5016791114 @default.
• W2212093853 creator A5016910789 @default.
• W2212093853 creator A5029810367 @default.
• W2212093853 date "1999-06-01" @default.
• W2212093853 modified "2023-10-18" @default.
• W2212093853 title "Skeletal muscle phosphocreatine recovery in exercise-trained humans is dependent on O₂availability" @default.
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• W2212093853 doi "https://doi.org/10.1152/jappl.1999.86.6.2013" @default.
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