Matches in SemOpenAlex for { <https://semopenalex.org/work/W2212152168> ?p ?o ?g. }
- W2212152168 endingPage "3385" @default.
- W2212152168 startingPage "3374" @default.
- W2212152168 abstract "Internal representations of action-outcome relationships are necessary for flexible adaptation of motivated behavior in dynamic environments. Prefrontal cortex (PFC) is implicated in flexible planning and execution of goal-directed actions, but little is known about how information about action-outcome relationships is represented across functionally distinct regions of PFC. Here, we observe distinct patterns of action-evoked single unit activity in the medial prefrontal cortex (mPFC) and orbitofrontal cortex (OFC) during a task in which the relationship between outcomes and actions was independently manipulated. The mPFC encoded changes in the number of actions required to earn a reward, but not fluctuations in outcome magnitude. In contrast, OFC neurons decreased firing rates as outcome magnitude was increased, but were insensitive to changes in action requirement. A subset of OFC neurons also tracked outcome availability. Pre-outcome anticipatory activity in both mPFC and OFC was altered when reward expectation was reduced, but did not differ with outcome magnitude. These data provide novel evidence that PFC regions encode distinct information about the relationship between actions and impending outcomes during action execution." @default.
- W2212152168 created "2016-06-24" @default.
- W2212152168 creator A5013802986 @default.
- W2212152168 creator A5055349297 @default.
- W2212152168 creator A5072457553 @default.
- W2212152168 date "2015-12-01" @default.
- W2212152168 modified "2023-10-17" @default.
- W2212152168 title "Action-outcome relationships are represented differently by medial prefrontal and orbitofrontal cortex neurons during action execution" @default.
- W2212152168 cites W1482139424 @default.
- W2212152168 cites W1527796392 @default.
- W2212152168 cites W1562703792 @default.
- W2212152168 cites W1565937950 @default.
- W2212152168 cites W1566698703 @default.
- W2212152168 cites W1749500062 @default.
- W2212152168 cites W1762920573 @default.
- W2212152168 cites W1939596644 @default.
- W2212152168 cites W1942802002 @default.
- W2212152168 cites W1950138029 @default.
- W2212152168 cites W1965407459 @default.
- W2212152168 cites W1966747638 @default.
- W2212152168 cites W1968159705 @default.
- W2212152168 cites W1969727558 @default.
- W2212152168 cites W1970448316 @default.
- W2212152168 cites W1971487556 @default.
- W2212152168 cites W1975401347 @default.
- W2212152168 cites W1977343782 @default.
- W2212152168 cites W1979942203 @default.
- W2212152168 cites W1990208186 @default.
- W2212152168 cites W1991097067 @default.
- W2212152168 cites W1992991285 @default.
- W2212152168 cites W1994297008 @default.
- W2212152168 cites W1998128125 @default.
- W2212152168 cites W2001488773 @default.
- W2212152168 cites W2005531913 @default.
- W2212152168 cites W2006346200 @default.
- W2212152168 cites W2019504975 @default.
- W2212152168 cites W2022264349 @default.
- W2212152168 cites W2022561239 @default.
- W2212152168 cites W2026148432 @default.
- W2212152168 cites W2028810361 @default.
- W2212152168 cites W2031534534 @default.
- W2212152168 cites W2033101096 @default.
- W2212152168 cites W2033423659 @default.
- W2212152168 cites W2036952324 @default.
- W2212152168 cites W2038564261 @default.
- W2212152168 cites W2052884866 @default.
- W2212152168 cites W2053003700 @default.
- W2212152168 cites W2056661320 @default.
- W2212152168 cites W2060783933 @default.
- W2212152168 cites W2064180977 @default.
- W2212152168 cites W2065291797 @default.
- W2212152168 cites W2065494210 @default.
- W2212152168 cites W2067976157 @default.
- W2212152168 cites W2070900790 @default.
- W2212152168 cites W2072009783 @default.
- W2212152168 cites W2073543631 @default.
- W2212152168 cites W2076860310 @default.
- W2212152168 cites W2078755291 @default.
- W2212152168 cites W2080530802 @default.
- W2212152168 cites W2081413820 @default.
- W2212152168 cites W2084913591 @default.
- W2212152168 cites W2086244298 @default.
- W2212152168 cites W2087809804 @default.
- W2212152168 cites W2090227765 @default.
- W2212152168 cites W2093071818 @default.
- W2212152168 cites W2093072166 @default.
- W2212152168 cites W2095108427 @default.
- W2212152168 cites W2095792916 @default.
- W2212152168 cites W2102810982 @default.
- W2212152168 cites W2103162253 @default.
- W2212152168 cites W2108018839 @default.
- W2212152168 cites W2111813559 @default.
- W2212152168 cites W2115752054 @default.
- W2212152168 cites W2116813115 @default.
- W2212152168 cites W2119757010 @default.
- W2212152168 cites W2120254525 @default.
- W2212152168 cites W2120520226 @default.
- W2212152168 cites W2121370521 @default.
- W2212152168 cites W2123429050 @default.
- W2212152168 cites W2126449078 @default.
- W2212152168 cites W2128192350 @default.
- W2212152168 cites W2129028793 @default.
- W2212152168 cites W2131624282 @default.
- W2212152168 cites W2136906168 @default.
- W2212152168 cites W2145183094 @default.
- W2212152168 cites W2146888468 @default.
- W2212152168 cites W2154658047 @default.
- W2212152168 cites W2157566327 @default.
- W2212152168 cites W2158052449 @default.
- W2212152168 cites W2159485971 @default.
- W2212152168 cites W2164912026 @default.
- W2212152168 cites W2166189176 @default.
- W2212152168 cites W2167785873 @default.
- W2212152168 cites W2169561465 @default.
- W2212152168 cites W2176421987 @default.
- W2212152168 cites W4296759584 @default.
- W2212152168 doi "https://doi.org/10.1152/jn.00884.2015" @default.
- W2212152168 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4868377" @default.