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- W2213168059 abstract "SummaryThe effects of x-irradiation on water, lipid and adenine-nucleotide contents of the rat liver and on the incorporation in vivo of inorganic 32P into liver adenine nucleotides have been studied. Irradiation was localized to a single hepatic lobe, the body and the remainder of the liver being shielded and used as control.30 min before killing at 3, 6 and 12 hours after irradiation, the animals were injected intraperitoneally with inorganic 32P-phosphate.Some experiments have been carried out on livers of total-body-irradiated rats killed after 6 hours.A comparison of the local irradiated lobes with the shielded portion of the same livers shows that:(1) the water content does not change;(2) lipid content is significantly increased 12 hours after the irradiation;(3) three hours after irradiation an increase in AMP concentration is observed. After 6 hours inorganic P, ADP and ATP contents are significantly increased. After 12 hours ATP concentration is raised;(4) at any time after the irradiation the incorporation of 32P into nucleotides is appreciably modified, except for an increase into ADP 3 hours after local irradiation.Total-body irradiation causes a significant increase of inorganic phosphorus level. The water, lipid and adenine-nucleotide contents are unmodified, and the incorporation of 32P into adenine nucleotides appears normal." @default.
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- W2213168059 date "1962-01-01" @default.
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- W2213168059 title "Effects of X-rays on Rat Liver: Behaviour of Adenine Nucleotides, Water and Total Lipids" @default.
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- W2213168059 doi "https://doi.org/10.1080/09553006214550671" @default.
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