Matches in SemOpenAlex for { <https://semopenalex.org/work/W2213238840> ?p ?o ?g. }
Showing items 1 to 71 of
71
with 100 items per page.
- W2213238840 endingPage "801" @default.
- W2213238840 startingPage "801" @default.
- W2213238840 abstract "ObjectiveThe aim of this study was to determine the histological changes of l-arginine-induced acute pancreatitis and the possible protective effect of pentoxifylline on pancreatic acini in adult male albino rats.BackgroundAcute pancreatitis is a reversible inflammation that is either localized to the pancreas or may spread to adjoining tissues.Materials and methodsForty adult male albino rats weighing 180-200 g each were used in this study. The rats were divided into four equal groups (10 rats each). Group I was the control group. In group II (l-arginine-treated), rats were administered two intraperitoneal injections of l-arginine at a dose of 200 mg/100 g/body weight with 1-h interval. They were randomly subdivided into two equal subgroups: in IIA, rats were killed after 24 h of the last l-arginine injection and in IIB, rats were killed after 1 week of the last l-arginine injection. In group III (l-arginine and pentoxifylline-treated), rats were administered l-arginine and pentoxifylline. l-arginine was given similar to group II and pentoxifylline was given as a single intraperitoneal injection at a dose of 12 mg/kg body weight/day. They were randomly subdivided into two equal subgroups: in IIIA, rats were given a single dose of pentoxifylline then were killed after 24 h and in subgroup IIIB, rats were given pentoxifylline daily for 1 week then were killed. In group IV (pentoxifylline-treated), rats were administered pentoxifylline as a single intraperitoneal injection of 12 mg/kg body weight/day for 1 week then rats were killed.Resultsl-arginine-treated rats for 24 h showed pancreatic edema, degenerative changes of pancreatic acini, and inflammatory cell infiltration. These changes were marked after 1 week; however, pentoxifylline supplementation in group III showed amelioration of the histological picture, which was marked after daily pentoxifylline treatment for a week.ConclusionIt is concluded that pentoxifylline was found to improve the histological changes of pancreatic acini caused by l-arginine." @default.
- W2213238840 created "2016-06-24" @default.
- W2213238840 creator A5010333149 @default.
- W2213238840 creator A5051043949 @default.
- W2213238840 creator A5055261982 @default.
- W2213238840 creator A5069559126 @default.
- W2213238840 creator A5087169415 @default.
- W2213238840 date "2014-01-01" @default.
- W2213238840 modified "2023-09-27" @default.
- W2213238840 title "Histological study on the possible protective effect of pentoxifylline on pancreatic acini of l-arginine-induced acute pancreatitis in adult male albino rats" @default.
- W2213238840 doi "https://doi.org/10.4103/1110-2098.149789" @default.
- W2213238840 hasPublicationYear "2014" @default.
- W2213238840 type Work @default.
- W2213238840 sameAs 2213238840 @default.
- W2213238840 citedByCount "3" @default.
- W2213238840 countsByYear W22132388402017 @default.
- W2213238840 countsByYear W22132388402018 @default.
- W2213238840 countsByYear W22132388402022 @default.
- W2213238840 crossrefType "journal-article" @default.
- W2213238840 hasAuthorship W2213238840A5010333149 @default.
- W2213238840 hasAuthorship W2213238840A5051043949 @default.
- W2213238840 hasAuthorship W2213238840A5055261982 @default.
- W2213238840 hasAuthorship W2213238840A5069559126 @default.
- W2213238840 hasAuthorship W2213238840A5087169415 @default.
- W2213238840 hasConcept C126322002 @default.
- W2213238840 hasConcept C134018914 @default.
- W2213238840 hasConcept C185592680 @default.
- W2213238840 hasConcept C2775967933 @default.
- W2213238840 hasConcept C2776670229 @default.
- W2213238840 hasConcept C2777468819 @default.
- W2213238840 hasConcept C2778764654 @default.
- W2213238840 hasConcept C2780159080 @default.
- W2213238840 hasConcept C2780404050 @default.
- W2213238840 hasConcept C2992926266 @default.
- W2213238840 hasConcept C515207424 @default.
- W2213238840 hasConcept C55493867 @default.
- W2213238840 hasConcept C71924100 @default.
- W2213238840 hasConceptScore W2213238840C126322002 @default.
- W2213238840 hasConceptScore W2213238840C134018914 @default.
- W2213238840 hasConceptScore W2213238840C185592680 @default.
- W2213238840 hasConceptScore W2213238840C2775967933 @default.
- W2213238840 hasConceptScore W2213238840C2776670229 @default.
- W2213238840 hasConceptScore W2213238840C2777468819 @default.
- W2213238840 hasConceptScore W2213238840C2778764654 @default.
- W2213238840 hasConceptScore W2213238840C2780159080 @default.
- W2213238840 hasConceptScore W2213238840C2780404050 @default.
- W2213238840 hasConceptScore W2213238840C2992926266 @default.
- W2213238840 hasConceptScore W2213238840C515207424 @default.
- W2213238840 hasConceptScore W2213238840C55493867 @default.
- W2213238840 hasConceptScore W2213238840C71924100 @default.
- W2213238840 hasIssue "4" @default.
- W2213238840 hasLocation W22132388401 @default.
- W2213238840 hasOpenAccess W2213238840 @default.
- W2213238840 hasPrimaryLocation W22132388401 @default.
- W2213238840 hasRelatedWork W1965534948 @default.
- W2213238840 hasRelatedWork W2033298711 @default.
- W2213238840 hasRelatedWork W2080520700 @default.
- W2213238840 hasRelatedWork W2213238840 @default.
- W2213238840 hasRelatedWork W2321903686 @default.
- W2213238840 hasRelatedWork W2352305283 @default.
- W2213238840 hasRelatedWork W2357466533 @default.
- W2213238840 hasRelatedWork W2358124812 @default.
- W2213238840 hasRelatedWork W2382880277 @default.
- W2213238840 hasRelatedWork W2394059641 @default.
- W2213238840 hasVolume "27" @default.
- W2213238840 isParatext "false" @default.
- W2213238840 isRetracted "false" @default.
- W2213238840 magId "2213238840" @default.
- W2213238840 workType "article" @default.