Matches in SemOpenAlex for { <https://semopenalex.org/work/W2213257954> ?p ?o ?g. }
Showing items 1 to 78 of
78
with 100 items per page.
- W2213257954 endingPage "13" @default.
- W2213257954 startingPage "1" @default.
- W2213257954 abstract "The objective of the present investigation was to study the protective role of aqueous extract of leaves of Moringa oleifera (MO) on nimesulide induced hepatotoxicity model in adult male albino rats. Hepatotoxicity in rats was caused by nimesulide at a dose of 10 mg/ml/kg body weight. Hepamerz, a drug used as standard hepatoprotective agent, was administered orally as standard hepatoprotective agent for 14 consecutive days prior to nimesulide treatment at a dose of 10mg/ml/kg body weight. This drug has many side effects. These side effects have prompted the scientific world for the search of alternative herbal based remedies of liver damage. The aqueous leaf extract of MO was administered orally to rats daily for 14 days before nimesulide treatment. The biochemical parameters were investigated. The results indicated that biochemical changes produced by nimesulide were restored to normal by aqueous extract of leaves of MO. The aqueous leaf extract of MO showed significant hepatoprotective effect through the modulation of antioxidant-mediated mechanism by altering serum glutamate oxaloacetate transaminase (SGOT), serum glutamate pyruvate transaminase (SGPT), alkaline phosphatase (ALP), superoxide dismutase (SOD) and catalase (CAT) activities and reduced glutathione (GSH) and lipid peroxidation (LPO) levels against nimesulide induced hepatotoxicity model in rats. The present study puts future research agenda of whether to implement the results on albino rats upon hepatoprotectivity in human body." @default.
- W2213257954 created "2016-06-24" @default.
- W2213257954 creator A5002314957 @default.
- W2213257954 creator A5034350620 @default.
- W2213257954 creator A5045305138 @default.
- W2213257954 date "2012-01-01" @default.
- W2213257954 modified "2023-09-27" @default.
- W2213257954 title "Protective role of moringa oleifera on nimesulide induced hepatotoxicity in albino rat model" @default.
- W2213257954 hasPublicationYear "2012" @default.
- W2213257954 type Work @default.
- W2213257954 sameAs 2213257954 @default.
- W2213257954 citedByCount "1" @default.
- W2213257954 countsByYear W22132579542013 @default.
- W2213257954 crossrefType "journal-article" @default.
- W2213257954 hasAuthorship W2213257954A5002314957 @default.
- W2213257954 hasAuthorship W2213257954A5034350620 @default.
- W2213257954 hasAuthorship W2213257954A5045305138 @default.
- W2213257954 hasConcept C160160445 @default.
- W2213257954 hasConcept C181199279 @default.
- W2213257954 hasConcept C185592680 @default.
- W2213257954 hasConcept C2775838275 @default.
- W2213257954 hasConcept C2776836740 @default.
- W2213257954 hasConcept C2777570176 @default.
- W2213257954 hasConcept C2778004101 @default.
- W2213257954 hasConcept C2778401633 @default.
- W2213257954 hasConcept C2778979269 @default.
- W2213257954 hasConcept C2780829032 @default.
- W2213257954 hasConcept C538909803 @default.
- W2213257954 hasConcept C55493867 @default.
- W2213257954 hasConcept C556039675 @default.
- W2213257954 hasConcept C71924100 @default.
- W2213257954 hasConcept C98274493 @default.
- W2213257954 hasConceptScore W2213257954C160160445 @default.
- W2213257954 hasConceptScore W2213257954C181199279 @default.
- W2213257954 hasConceptScore W2213257954C185592680 @default.
- W2213257954 hasConceptScore W2213257954C2775838275 @default.
- W2213257954 hasConceptScore W2213257954C2776836740 @default.
- W2213257954 hasConceptScore W2213257954C2777570176 @default.
- W2213257954 hasConceptScore W2213257954C2778004101 @default.
- W2213257954 hasConceptScore W2213257954C2778401633 @default.
- W2213257954 hasConceptScore W2213257954C2778979269 @default.
- W2213257954 hasConceptScore W2213257954C2780829032 @default.
- W2213257954 hasConceptScore W2213257954C538909803 @default.
- W2213257954 hasConceptScore W2213257954C55493867 @default.
- W2213257954 hasConceptScore W2213257954C556039675 @default.
- W2213257954 hasConceptScore W2213257954C71924100 @default.
- W2213257954 hasConceptScore W2213257954C98274493 @default.
- W2213257954 hasIssue "8" @default.
- W2213257954 hasLocation W22132579541 @default.
- W2213257954 hasOpenAccess W2213257954 @default.
- W2213257954 hasPrimaryLocation W22132579541 @default.
- W2213257954 hasRelatedWork W1574290932 @default.
- W2213257954 hasRelatedWork W1588924907 @default.
- W2213257954 hasRelatedWork W1647489763 @default.
- W2213257954 hasRelatedWork W1987448528 @default.
- W2213257954 hasRelatedWork W1996696912 @default.
- W2213257954 hasRelatedWork W2061018041 @default.
- W2213257954 hasRelatedWork W2067774006 @default.
- W2213257954 hasRelatedWork W2076789176 @default.
- W2213257954 hasRelatedWork W2078735863 @default.
- W2213257954 hasRelatedWork W2226914192 @default.
- W2213257954 hasRelatedWork W2242989110 @default.
- W2213257954 hasRelatedWork W2254228337 @default.
- W2213257954 hasRelatedWork W2265217173 @default.
- W2213257954 hasRelatedWork W2402526251 @default.
- W2213257954 hasRelatedWork W2472649303 @default.
- W2213257954 hasRelatedWork W2593104297 @default.
- W2213257954 hasRelatedWork W3008255527 @default.
- W2213257954 hasRelatedWork W78191812 @default.
- W2213257954 hasRelatedWork W2240251766 @default.
- W2213257954 hasRelatedWork W2395493164 @default.
- W2213257954 hasVolume "2" @default.
- W2213257954 isParatext "false" @default.
- W2213257954 isRetracted "false" @default.
- W2213257954 magId "2213257954" @default.
- W2213257954 workType "article" @default.