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- W2213306586 abstract "Publisher Summary This chapter clarifies the possible role of interhemispheric inhibition on motor cortex reorganization in the nonstroke hemisphere. To address this problem excitatory and inhibitory effect of focal transcranial magnetic stimulation (TMS) over the motor cortex in patients with differently localized monohemispheric stroke were investigated. Ischemic cortical and subcortical lesions were used as a model for studying the effects of impaired interhemispheric inhibition on neuronal function in the opposite, intact motor cortex. Functional integrity of the interhemispheric connections was assessed by transcallosal inhibition (TI) of voluntary tonic electromyographic activity elicited by TMS. In patients with stroke, both poor and good motor recovery associated with an abnormal excitability over the unaffected hemisphere has been reported. The clinical relevance of motor cortex disinhibition in the undamaged hemisphere needs to be elucidated. The findings document that in acute stroke a loss of interhemispheric inhibition may induce motor cortex disinhibition in the undamaged hemisphere." @default.
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- W2213306586 date "2003-01-01" @default.
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- W2213306586 title "Chapter 17 Impact of interhemispheric inhibition on excitability of the non-lesioned motor cortex after acute stroke" @default.
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- W2213306586 doi "https://doi.org/10.1016/s1567-424x(09)70220-x" @default.
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