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• W2213776894 abstract "We evaluated the fraction of variation in HIV-1 set point viral load attributable to viral or human genetic factors by using joint host/pathogen genetic data from 541 HIV infected individuals. We show that viral genetic diversity explains 29% of the variation in viral load while host factors explain 8.4%. Using a joint model including both host and viral effects, we estimate a total of 30% heritability, indicating that most of the host effects are reflected in viral sequence variation." @default.
• W2213776894 created "2016-06-24" @default.
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• W2213776894 date "2017-02-09" @default.
• W2213776894 modified "2023-10-05" @default.
• W2213776894 title "Estimating the Respective Contributions of Human and Viral Genetic Variation to HIV Control" @default.
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• W2213776894 doi "https://doi.org/10.1371/journal.pcbi.1005339" @default.
• W2213776894 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5300119" @default.
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• W2213776894 hasPublicationYear "2017" @default.
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