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- W2214018468 abstract "Lactobacillus plantarum species often harbor several plasmids. These plasmids may encodedimportant traits such as phages or antibiotics resistances, lactose catabolism and production ofproteolytic enzyme and also bacteriocins that named plantaricin. Lactobacillus plantarum IBL-2that isolated from strawberry of Bali plantation have the highest anti-microorganism activityamong the L. plantarum isolate collection of BTCC Indonesia. Only few study carried out toexamine the antifungal activity of bacteriocin from L. plantarum. This study focus on anti-Candidaactivity of plasmid associated with bacteriocin production from L. plantarum IBL-2. The isolateswere confirmed by the 16S rRNA analysis by PCR and the phylogenetic tree was built based onreferences sequences and one outgroups from database. The plantaricin gene screening thenperformed in plasmid that was isolated from L. plantarum IBL-2 by PCR using five pairs orplantaricin gene primer. The anti-Candida potential of plantaricin observed were analyzed byin silico by docking analysis between the plantaricin and receptors of apoptosis proteins. PlnB andPlnEF were observed in the L. plantarum plasmid. Only PlnEF become the focus of study. Analysisof docking study predicted that PlnEF have interactions with apoptosis proteins regulator ineukaryotic cells. PlnEF that encoded by plasmid of L. plantarum may exert anti-Candida potentialthrough interactions with apoptosis proteins regulator." @default.
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- W2214018468 date "2015-12-01" @default.
- W2214018468 modified "2023-09-29" @default.
- W2214018468 title "In Silico Analysis of Plantaricin EF that Expressed by Plasmid-Associated Bacteriocin Production Gene of Lactobacillus plantarum IBL-2 for Anti-Candida Agent Potential" @default.
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- W2214018468 doi "https://doi.org/10.3923/jm.2015.582.591" @default.
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