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- W2214086181 abstract "Chronic alcohol intake accounts for 60-90% of the cases of chronic pancreatitis, but other etiologies have been recognized and described in the very recent years. Genetic causes include mutations of the cationic trypsinogen gene PRSS1 (100 families in France), of its inhibitor SPINK1 and of the CFTR gene involved in cystic fibrosis. Auto-immune pancreatitis is often part of an IgG4-related systemic disease involving the biliary tract, the salivary glands, the retroperitoneum and/or the kidneys. Diagnostic criteria are now well-defined (HISORt of the Mayo Clinic), with ductal and parenchymal lesions on imaging that may mimick pancreatic adenocarcinoma. Corticoids are efficacious but recurrences are frequent and long-term outcome is still poorly known." @default.
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- W2214086181 date "2009-08-01" @default.
- W2214086181 modified "2023-09-26" @default.
- W2214086181 title "De la pancréatite chronique aux pancréatites chroniques" @default.
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- W2214086181 doi "https://doi.org/10.1016/j.gcb.2009.07.017" @default.
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