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- W2214182608 abstract "2733 Objectives Contrary to our department Lugol patient procedure policy (two day regimen), I-123 DaTscan product insert recommends a one day Lugol regimen. Our laboratory evaluated the differences in thyroid uptake in patients receiving Lugol’s solution the day prior to and the day of I-123 DaTscan administration versus patients receiving Lugol’s solution one hour prior to administration. Methods A total of 13 DaTscan patients were studied. The first group of patients (n=5) received a two-day Lugol regimen (the day before and the day of I-123 administration). A second group of patients (n=8) received a one-day dose (one hour prior to I-123 administration). All patients were injected with 4.4-5.1 mCi I-123 DaTscan. Residual syringe activity was measured to determine the exact activity administered. At four hours after injection, a 10 minute thyroid image was obtained prior to initiating I-123 DaTscan studies. Regions of interest were drawn around thyroid images to obtain thyroid uptake counts. An I-123 standard was used to quantify thyroid counts and the percent thyroid uptake calculated from decayed administered activity. Statistical analysis was performed (t-test) to determine significant differences between the two patient groups. Results Thyroid uptake in I-123 DaTscan patients (n=8) who received a one-day Lugol regimen ranged from 2.2% to 4.0%. Thyroid uptake in I-123 DaTscan patients (n=5) who received a two-day Lugol regimen ranged from 2.6% to 3.2%. Statistical analysis of the two groups demonstrated no significant differences (p=0.05) between a one-day and a two-day Lugol regimen. Conclusions The effect of one day vs two day Lugol regimen in patients receiving I-123 DaTscan was investigated. No statistically significant differences between patient groups was observed. For patient convenience, our laboratory has adapted a one day Lugol regimen for patients receiving I-123 DaTscan." @default.
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- W2214182608 date "2014-05-01" @default.
- W2214182608 modified "2023-09-23" @default.
- W2214182608 title "I-123 DaTscan imaging: Effects of Lugol patient preparations on thyroid uptake" @default.
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