Matches in SemOpenAlex for { <https://semopenalex.org/work/W2214187767> ?p ?o ?g. }
Showing items 1 to 75 of
75
with 100 items per page.
- W2214187767 endingPage "931" @default.
- W2214187767 startingPage "931" @default.
- W2214187767 abstract "Abdominal aortic aneurysm (AAA) is often asymptomatic until rupture occurs. Although ultrasound screening has significantly improved the early diagnosis of AAA, the timely biomarker-based diagnosis of AAA remains a major clinical challenge. In this study, we aimed to assess plasma microRNAs (miRNAs) as promising novel biomarkers in patients with AAA.Pooled plasma samples from 10 AAA and 10 healthy controls were profiled by microarray. The differentially expressed miRNAs were evaluated in a separate cohort of 120 subjects, including 60 AAA patients and 60 normal controls.The initial profiling study identified 151 miRNAs that showed more than two-fold change. Among them, three miRNAs, miR-191-3p, miR-455-3p and miR-1281 exhibited the largest increase in the patient group (fold change > 5). A subsequent validation study confirmed the elevation of these three miRNAs. Receiver operator characteristic curve analysis using the expression ratio of miR-191-3p, miR-455-3p and miR-1281 showed an area under the curve of 0.9700, 0.9825 and 0.9206, respectively.Our results suggest that plasma miR-191-3p, miR-455-3p and miR-1281 may be used as potential diagnosis biomarkers for AAA." @default.
- W2214187767 created "2016-06-24" @default.
- W2214187767 creator A5030099116 @default.
- W2214187767 creator A5034876492 @default.
- W2214187767 date "2015-10-01" @default.
- W2214187767 modified "2023-09-26" @default.
- W2214187767 title "Circulating Nucleic Acids Special Issue" @default.
- W2214187767 doi "https://doi.org/10.1016/j.clinbiochem.2015.08.021" @default.
- W2214187767 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26315671" @default.
- W2214187767 hasPublicationYear "2015" @default.
- W2214187767 type Work @default.
- W2214187767 sameAs 2214187767 @default.
- W2214187767 citedByCount "1" @default.
- W2214187767 countsByYear W22141877672015 @default.
- W2214187767 crossrefType "journal-article" @default.
- W2214187767 hasAuthorship W2214187767A5030099116 @default.
- W2214187767 hasAuthorship W2214187767A5034876492 @default.
- W2214187767 hasConcept C104317684 @default.
- W2214187767 hasConcept C126322002 @default.
- W2214187767 hasConcept C141071460 @default.
- W2214187767 hasConcept C143998085 @default.
- W2214187767 hasConcept C145059251 @default.
- W2214187767 hasConcept C150194340 @default.
- W2214187767 hasConcept C186836561 @default.
- W2214187767 hasConcept C2776098176 @default.
- W2214187767 hasConcept C2777910003 @default.
- W2214187767 hasConcept C2779018089 @default.
- W2214187767 hasConcept C2779993416 @default.
- W2214187767 hasConcept C2781197716 @default.
- W2214187767 hasConcept C54355233 @default.
- W2214187767 hasConcept C58471807 @default.
- W2214187767 hasConcept C60644358 @default.
- W2214187767 hasConcept C71924100 @default.
- W2214187767 hasConcept C86803240 @default.
- W2214187767 hasConcept C90924648 @default.
- W2214187767 hasConceptScore W2214187767C104317684 @default.
- W2214187767 hasConceptScore W2214187767C126322002 @default.
- W2214187767 hasConceptScore W2214187767C141071460 @default.
- W2214187767 hasConceptScore W2214187767C143998085 @default.
- W2214187767 hasConceptScore W2214187767C145059251 @default.
- W2214187767 hasConceptScore W2214187767C150194340 @default.
- W2214187767 hasConceptScore W2214187767C186836561 @default.
- W2214187767 hasConceptScore W2214187767C2776098176 @default.
- W2214187767 hasConceptScore W2214187767C2777910003 @default.
- W2214187767 hasConceptScore W2214187767C2779018089 @default.
- W2214187767 hasConceptScore W2214187767C2779993416 @default.
- W2214187767 hasConceptScore W2214187767C2781197716 @default.
- W2214187767 hasConceptScore W2214187767C54355233 @default.
- W2214187767 hasConceptScore W2214187767C58471807 @default.
- W2214187767 hasConceptScore W2214187767C60644358 @default.
- W2214187767 hasConceptScore W2214187767C71924100 @default.
- W2214187767 hasConceptScore W2214187767C86803240 @default.
- W2214187767 hasConceptScore W2214187767C90924648 @default.
- W2214187767 hasIssue "15" @default.
- W2214187767 hasLocation W22141877671 @default.
- W2214187767 hasLocation W22141877672 @default.
- W2214187767 hasOpenAccess W2214187767 @default.
- W2214187767 hasPrimaryLocation W22141877671 @default.
- W2214187767 hasRelatedWork W1974699429 @default.
- W2214187767 hasRelatedWork W2021120647 @default.
- W2214187767 hasRelatedWork W2899824740 @default.
- W2214187767 hasRelatedWork W2921209636 @default.
- W2214187767 hasRelatedWork W2988116615 @default.
- W2214187767 hasRelatedWork W2991124544 @default.
- W2214187767 hasRelatedWork W3035558492 @default.
- W2214187767 hasRelatedWork W3165010514 @default.
- W2214187767 hasRelatedWork W3176043644 @default.
- W2214187767 hasRelatedWork W4248768796 @default.
- W2214187767 hasVolume "48" @default.
- W2214187767 isParatext "false" @default.
- W2214187767 isRetracted "false" @default.
- W2214187767 magId "2214187767" @default.
- W2214187767 workType "article" @default.