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• W2214306521 abstract "A progressive decrease was observed in the 5-methyldeoxycytidine content of hepatic DNA in male F344 rats fed with a hepatocarcinogenic methyl-deficient diet. The same dietary regimen resulted in altered hepatic contents of S-adenosylmethionine, the methyl-donating species, and S-adenosylhomocysteine, an inhibitor of DNA methylase. The data indicate that this carcinogenic dietary manipulation is sufficient to alter a possible regulatory process, DNA methylation." @default.
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• W2214306521 date "1984-03-15" @default.
• W2214306521 modified "2023-09-23" @default.
• W2214306521 title "Hypomethylation of hepatic nuclear DNA in rats fed with a carcinogenic methyl-deficient diet" @default.
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• W2214306521 doi "https://doi.org/10.1042/bj2180987" @default.
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