Matches in SemOpenAlex for { <https://semopenalex.org/work/W2214443020> ?p ?o ?g. }
- W2214443020 endingPage "95" @default.
- W2214443020 startingPage "88" @default.
- W2214443020 abstract "Adequate hydration is recommended for acute ST-elevation myocardial infarction (STEMI) patients undergoing primary percutaneous coronary intervention (PCI) to prevent contrast-induced nephropathy (CIN). However, the optimal hydration regimen has not been well established in these high-risk patients. The objective of this study is to evaluate the efficacy of a preprocedural loading dose plus postprocedural aggressive hydration with normal saline guided by the left ventricular end-diastolic pressure (LVEDP) compared with general hydration for CIN prevention. The ATTEMPT study is a multicenter, open-label, investigator-driven, randomized controlled trial in China. Approximately 560 patients with STEMI undergoing primary PCI will be randomized (1:1) to receive either periprocedural general hydration (control group) or aggressive hydration (treatment group). Patients in the control group receive periprocedural general hydration with ≤500 mL normal saline (within 6 hours) at a normal rate (0.5 or 1 mL/kg · h). Patients in the treatment group receive a preprocedural loading dose (125/250 mL) of normal saline within 30 minutes and intravenous hydration at a normal rate until LVEDP is available, followed by postprocedural aggressive hydration guided by LVEDP for 4 hours and then continuous intravascular hydration at the normal rate until 24 hours after PCI. The primary end point is CIN, defined as a >25% or 0.5-mg/dL increase in serum creatinine from baseline during the first 48 to 72 hours after procedure. The ATTEMPT study has the potential to identify optimal hydration regimens for STEMI patients undergoing PCI." @default.
- W2214443020 created "2016-06-24" @default.
- W2214443020 creator A5012491543 @default.
- W2214443020 creator A5021239241 @default.
- W2214443020 creator A5034764782 @default.
- W2214443020 creator A5040240835 @default.
- W2214443020 creator A5051396544 @default.
- W2214443020 creator A5064178924 @default.
- W2214443020 creator A5069265327 @default.
- W2214443020 creator A5080427269 @default.
- W2214443020 creator A5087403596 @default.
- W2214443020 date "2016-02-01" @default.
- W2214443020 modified "2023-09-25" @default.
- W2214443020 title "Aggressive hydraTion in patients with ST-Elevation Myocardial infarction undergoing Primary percutaneous coronary intervention to prevenT contrast-induced nephropathy (ATTEMPT): Study design and protocol for the randomized, controlled trial, the ATTEMPT, RESCIND 1 (First study for REduction of contraSt-induCed nephropathy followINg carDiac catheterization) trial" @default.
- W2214443020 cites W115559861 @default.
- W2214443020 cites W1976081980 @default.
- W2214443020 cites W1983463589 @default.
- W2214443020 cites W1984230906 @default.
- W2214443020 cites W1997197503 @default.
- W2214443020 cites W2004105866 @default.
- W2214443020 cites W2005583134 @default.
- W2214443020 cites W2005849560 @default.
- W2214443020 cites W2014642694 @default.
- W2214443020 cites W2020818036 @default.
- W2214443020 cites W2022183856 @default.
- W2214443020 cites W2024823566 @default.
- W2214443020 cites W2025388408 @default.
- W2214443020 cites W2031040175 @default.
- W2214443020 cites W2061514693 @default.
- W2214443020 cites W2064639320 @default.
- W2214443020 cites W2077929901 @default.
- W2214443020 cites W2088266620 @default.
- W2214443020 cites W2096277043 @default.
- W2214443020 cites W2097637956 @default.
- W2214443020 cites W2101484943 @default.
- W2214443020 cites W2116898738 @default.
- W2214443020 cites W2128817169 @default.
- W2214443020 cites W2130212124 @default.
- W2214443020 cites W2130266388 @default.
- W2214443020 cites W2137158992 @default.
- W2214443020 cites W2148635490 @default.
- W2214443020 cites W2154140731 @default.
- W2214443020 cites W2157672682 @default.
- W2214443020 cites W2161200062 @default.
- W2214443020 cites W2161321523 @default.
- W2214443020 cites W2165175233 @default.
- W2214443020 cites W2330000101 @default.
- W2214443020 cites W2548894639 @default.
- W2214443020 cites W4230152141 @default.
- W2214443020 cites W4234395934 @default.
- W2214443020 cites W4236531408 @default.
- W2214443020 cites W4293372203 @default.
- W2214443020 doi "https://doi.org/10.1016/j.ahj.2015.10.007" @default.
- W2214443020 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26856220" @default.
- W2214443020 hasPublicationYear "2016" @default.
- W2214443020 type Work @default.
- W2214443020 sameAs 2214443020 @default.
- W2214443020 citedByCount "16" @default.
- W2214443020 countsByYear W22144430202017 @default.
- W2214443020 countsByYear W22144430202018 @default.
- W2214443020 countsByYear W22144430202019 @default.
- W2214443020 countsByYear W22144430202020 @default.
- W2214443020 countsByYear W22144430202021 @default.
- W2214443020 countsByYear W22144430202022 @default.
- W2214443020 crossrefType "journal-article" @default.
- W2214443020 hasAuthorship W2214443020A5012491543 @default.
- W2214443020 hasAuthorship W2214443020A5021239241 @default.
- W2214443020 hasAuthorship W2214443020A5034764782 @default.
- W2214443020 hasAuthorship W2214443020A5040240835 @default.
- W2214443020 hasAuthorship W2214443020A5051396544 @default.
- W2214443020 hasAuthorship W2214443020A5064178924 @default.
- W2214443020 hasAuthorship W2214443020A5069265327 @default.
- W2214443020 hasAuthorship W2214443020A5080427269 @default.
- W2214443020 hasAuthorship W2214443020A5087403596 @default.
- W2214443020 hasConcept C126322002 @default.
- W2214443020 hasConcept C141071460 @default.
- W2214443020 hasConcept C164705383 @default.
- W2214443020 hasConcept C168563851 @default.
- W2214443020 hasConcept C178853913 @default.
- W2214443020 hasConcept C203092338 @default.
- W2214443020 hasConcept C2777397205 @default.
- W2214443020 hasConcept C2778569047 @default.
- W2214443020 hasConcept C2780400711 @default.
- W2214443020 hasConcept C42219234 @default.
- W2214443020 hasConcept C45393284 @default.
- W2214443020 hasConcept C48277249 @default.
- W2214443020 hasConcept C500558357 @default.
- W2214443020 hasConcept C71924100 @default.
- W2214443020 hasConceptScore W2214443020C126322002 @default.
- W2214443020 hasConceptScore W2214443020C141071460 @default.
- W2214443020 hasConceptScore W2214443020C164705383 @default.
- W2214443020 hasConceptScore W2214443020C168563851 @default.
- W2214443020 hasConceptScore W2214443020C178853913 @default.
- W2214443020 hasConceptScore W2214443020C203092338 @default.
- W2214443020 hasConceptScore W2214443020C2777397205 @default.
- W2214443020 hasConceptScore W2214443020C2778569047 @default.
- W2214443020 hasConceptScore W2214443020C2780400711 @default.
- W2214443020 hasConceptScore W2214443020C42219234 @default.