FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2214462827> ?p ?o ?g. }

• W2214462827 endingPage "50" @default.
• W2214462827 startingPage "43" @default.
• W2214462827 abstract "Cationic lipid-like molecules (lipidoids) are widely used for in vitro and in vivo gene delivery. Nearly all lipidoids developed to date employ double-tail or multiple-tail structures for transfection. Single-tail lipidoids are seldom considered for transfection as they have low efficiency in gene delivery. So far, there is no detailed study on the contribution to transfection efficiency of single-tail lipidoids when combined with standard double-tail lipidoids. Here, we use combinatorial chemistry to synthesize 17 double-tail and 17 single-tail lipidoids using thiol–yne and thiol–ene click chemistry, respectively. HEK 293T cells were used to analyze transfection efficiency by fluorescence microscopy and calculated based on the percentage of cells transfected. The size and zeta potential of liposomes and lipoplexes were characterized by dynamic light scattering (DLS). Intracellular DNA delivery and trafficking was further examined using confocal microscopy. Our study shows that combining single with double-tail lipidoids increases uptake of lipoplexes, as well as cellular transfection efficiency." @default.
• W2214462827 created "2016-06-24" @default.
• W2214462827 creator A5030453754 @default.
• W2214462827 creator A5044198505 @default.
• W2214462827 creator A5050237707 @default.
• W2214462827 creator A5050303674 @default.
• W2214462827 creator A5062049260 @default.
• W2214462827 creator A5075955593 @default.
• W2214462827 date "2015-12-24" @default.
• W2214462827 modified "2023-09-24" @default.
• W2214462827 title "Single-Tailed Lipidoids Enhance the Transfection Activity of Their Double-Tailed Counterparts" @default.
• W2214462827 cites W1481565655 @default.
• W2214462827 cites W1971982338 @default.
• W2214462827 cites W1984564687 @default.
• W2214462827 cites W2002151233 @default.
• W2214462827 cites W2006202262 @default.
• W2214462827 cites W2014356856 @default.
• W2214462827 cites W2015696531 @default.
• W2214462827 cites W2034342858 @default.
• W2214462827 cites W2039551908 @default.
• W2214462827 cites W2056833586 @default.
• W2214462827 cites W2058953370 @default.
• W2214462827 cites W2059688446 @default.
• W2214462827 cites W2060221489 @default.
• W2214462827 cites W2073026167 @default.
• W2214462827 cites W2073697450 @default.
• W2214462827 cites W2073763250 @default.
• W2214462827 cites W2075279905 @default.
• W2214462827 cites W2076163624 @default.
• W2214462827 cites W2077850392 @default.
• W2214462827 cites W2078483179 @default.
• W2214462827 cites W2081644109 @default.
• W2214462827 cites W2082927803 @default.
• W2214462827 cites W2089150369 @default.
• W2214462827 cites W2105106090 @default.
• W2214462827 cites W2107554012 @default.
• W2214462827 cites W2128878122 @default.
• W2214462827 cites W2155534998 @default.
• W2214462827 cites W2171279500 @default.
• W2214462827 cites W2313457734 @default.
• W2214462827 cites W2318309737 @default.
• W2214462827 cites W2322131483 @default.
• W2214462827 doi "https://doi.org/10.1021/acscombsci.5b00117" @default.
• W2214462827 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26651853" @default.
• W2214462827 hasPublicationYear "2015" @default.
• W2214462827 type Work @default.
• W2214462827 sameAs 2214462827 @default.
• W2214462827 citedByCount "8" @default.
• W2214462827 countsByYear W22144628272018 @default.
• W2214462827 countsByYear W22144628272019 @default.
• W2214462827 countsByYear W22144628272020 @default.
• W2214462827 countsByYear W22144628272021 @default.
• W2214462827 countsByYear W22144628272022 @default.
• W2214462827 countsByYear W22144628272023 @default.
• W2214462827 crossrefType "journal-article" @default.
• W2214462827 hasAuthorship W2214462827A5030453754 @default.
• W2214462827 hasAuthorship W2214462827A5044198505 @default.
• W2214462827 hasAuthorship W2214462827A5050237707 @default.
• W2214462827 hasAuthorship W2214462827A5050303674 @default.
• W2214462827 hasAuthorship W2214462827A5062049260 @default.
• W2214462827 hasAuthorship W2214462827A5075955593 @default.
• W2214462827 hasConcept C104317684 @default.
• W2214462827 hasConcept C121332964 @default.
• W2214462827 hasConcept C12554922 @default.
• W2214462827 hasConcept C135983454 @default.
• W2214462827 hasConcept C153911025 @default.
• W2214462827 hasConcept C155887181 @default.
• W2214462827 hasConcept C169274487 @default.
• W2214462827 hasConcept C174510640 @default.
• W2214462827 hasConcept C185154212 @default.
• W2214462827 hasConcept C185592680 @default.
• W2214462827 hasConcept C202751555 @default.
• W2214462827 hasConcept C207001950 @default.
• W2214462827 hasConcept C2779178360 @default.
• W2214462827 hasConcept C54009773 @default.
• W2214462827 hasConcept C54355233 @default.
• W2214462827 hasConcept C55493867 @default.
• W2214462827 hasConcept C62520636 @default.
• W2214462827 hasConcept C79879829 @default.
• W2214462827 hasConcept C86803240 @default.
• W2214462827 hasConcept C91881484 @default.
• W2214462827 hasConcept C95444343 @default.
• W2214462827 hasConceptScore W2214462827C104317684 @default.
• W2214462827 hasConceptScore W2214462827C121332964 @default.
• W2214462827 hasConceptScore W2214462827C12554922 @default.
• W2214462827 hasConceptScore W2214462827C135983454 @default.
• W2214462827 hasConceptScore W2214462827C153911025 @default.
• W2214462827 hasConceptScore W2214462827C155887181 @default.
• W2214462827 hasConceptScore W2214462827C169274487 @default.
• W2214462827 hasConceptScore W2214462827C174510640 @default.
• W2214462827 hasConceptScore W2214462827C185154212 @default.
• W2214462827 hasConceptScore W2214462827C185592680 @default.
• W2214462827 hasConceptScore W2214462827C202751555 @default.
• W2214462827 hasConceptScore W2214462827C207001950 @default.
• W2214462827 hasConceptScore W2214462827C2779178360 @default.
• W2214462827 hasConceptScore W2214462827C54009773 @default.
• W2214462827 hasConceptScore W2214462827C54355233 @default.
• W2214462827 hasConceptScore W2214462827C55493867 @default.

• next