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- W2214700129 abstract "Goal. To evaluate the clinical effect of early administration of surfactant-BL on pulmonary oxygenizing function and biomechanics in patients early after lung transplantation (LT). Materials and methods. Seven patients early after transplantation were administered with a surfactant-BL («Biosurf», St.-Petersburg, RF) to prevent or treat primary lung transplant disfunction. Results and conclusions. Multiple endobronchial administration of surfactant-BL (0, 24, and 48 hours) resulted in a progressive increase in the ratio of arterial oxygen partial pressure by an average of 94 mm Hg (p<0.05) to oxygen fraction in a respiratory mixture ( РаО2^Ю2) at 48 hours after the surgery and by an average 1.2-fold increase in dynamic thoracopulmonary compliance accompanied by a reduction in the magnitude of PLGD. Employed protocol of surfactant-BL administration was favorable for optimizing the biomechanical properties and oxygenizing function of the lung. The findings clearly demonstrate that the early administration of surfactant-BL after LT should benefit the comprehensive prevention and treatment of PLGD that complicates the early postoperative period after LT." @default.
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- W2214700129 date "2013-04-20" @default.
- W2214700129 modified "2023-09-26" @default.
- W2214700129 title "Early Use of Surfactant-BL after Lung Transplantation" @default.
- W2214700129 doi "https://doi.org/10.15360/1813-9779-2013-2-12" @default.
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