FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2214763145> ?p ?o ?g. }

• W2214763145 endingPage "842" @default.
• W2214763145 startingPage "833" @default.
• W2214763145 abstract "The expression of mouse mammary tumor virus (MMTV) glycoproteins on the surface of stably infected mouse lymphoma cell line W7MG1 is dramatically increased by glucocorticoid hormones. A variant cell line, W7M.TS1, was selected from W7MG1 for its lack of expression of MMTV glycoproteins on the cell surface in response to treatment with glucocorticoid. Hormonal stimulation of MMTV RNA levels and hormone-induced cytolysis occurred normally in the variant cells. Furthermore, the rates of production of the precursor and mature forms of MMTV glycoproteins in the presence of glucocorticoid were similar in variant and wild-type cells. However, the accumulation of MMTV glycoproteins on the cell surface after hormone treatment was delayed by about 8 h in the variant relative to wild-type cells. The steady-state level of a constitutively expressed cellular protein, T200, on the variant cell surface was comparable to that on wild-type cells. However, in pulse-chase experiments, the appearance of newly synthesized T200 on the cell surface was delayed in the variant compared with wild-type cells. Another glucocorticoid hormone response, removal of H-2 class I antigens from the cell surface, was also delayed in the variant relative to wild-type cells, suggesting that turnover or internalization of cell surface glycoproteins may also be affected in the variant. The defects in the variant cell line were observed at 37 degrees C, but not at 31 degrees C; the variant cells grew normally at both temperatures. This variant phenotype defines a new genetic entity that is important for transport of glycoproteins between internal microsomal compartments and the cell surface." @default.
• W2214763145 created "2016-06-24" @default.
• W2214763145 creator A5015583839 @default.
• W2214763145 creator A5038137463 @default.
• W2214763145 date "1988-02-01" @default.
• W2214763145 modified "2023-09-27" @default.
• W2214763145 title "Temperature-sensitive transport of glycoproteins to the surface of a variant mouse lymphoma cell line." @default.
• W2214763145 cites W106235760 @default.
• W2214763145 cites W1487090760 @default.
• W2214763145 cites W1493185078 @default.
• W2214763145 cites W1510707687 @default.
• W2214763145 cites W1523542926 @default.
• W2214763145 cites W1816727596 @default.
• W2214763145 cites W1964274593 @default.
• W2214763145 cites W1986676191 @default.
• W2214763145 cites W2005375212 @default.
• W2214763145 cites W2021272662 @default.
• W2214763145 cites W2021956984 @default.
• W2214763145 cites W2027536811 @default.
• W2214763145 cites W2039115958 @default.
• W2214763145 cites W2049057593 @default.
• W2214763145 cites W2053452944 @default.
• W2214763145 cites W2058168439 @default.
• W2214763145 cites W2070691419 @default.
• W2214763145 cites W2071427211 @default.
• W2214763145 cites W2079687293 @default.
• W2214763145 cites W2083263961 @default.
• W2214763145 cites W2086376430 @default.
• W2214763145 cites W2087737282 @default.
• W2214763145 cites W2091417035 @default.
• W2214763145 cites W2092057385 @default.
• W2214763145 cites W2100990082 @default.
• W2214763145 cites W2109189984 @default.
• W2214763145 cites W2112210750 @default.
• W2214763145 cites W2126910751 @default.
• W2214763145 cites W2133449590 @default.
• W2214763145 cites W2146703639 @default.
• W2214763145 cites W2149736282 @default.
• W2214763145 cites W2152708819 @default.
• W2214763145 cites W2169790726 @default.
• W2214763145 cites W2174160083 @default.
• W2214763145 cites W2175970545 @default.
• W2214763145 cites W2178769189 @default.
• W2214763145 cites W2412941035 @default.
• W2214763145 cites W2492458449 @default.
• W2214763145 cites W2461054369 @default.
• W2214763145 doi "https://doi.org/10.1128/mcb.8.2.833" @default.
• W2214763145 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/363214" @default.
• W2214763145 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2832739" @default.
• W2214763145 hasPublicationYear "1988" @default.
• W2214763145 type Work @default.
• W2214763145 sameAs 2214763145 @default.
• W2214763145 citedByCount "0" @default.
• W2214763145 crossrefType "journal-article" @default.
• W2214763145 hasAuthorship W2214763145A5015583839 @default.
• W2214763145 hasAuthorship W2214763145A5038137463 @default.
• W2214763145 hasBestOaLocation W22147631452 @default.
• W2214763145 hasConcept C108625454 @default.
• W2214763145 hasConcept C134018914 @default.
• W2214763145 hasConcept C1491633281 @default.
• W2214763145 hasConcept C153911025 @default.
• W2214763145 hasConcept C154317977 @default.
• W2214763145 hasConcept C159047783 @default.
• W2214763145 hasConcept C202751555 @default.
• W2214763145 hasConcept C2522874641 @default.
• W2214763145 hasConcept C2779777497 @default.
• W2214763145 hasConcept C2780841215 @default.
• W2214763145 hasConcept C54355233 @default.
• W2214763145 hasConcept C55493867 @default.
• W2214763145 hasConcept C73588182 @default.
• W2214763145 hasConcept C81885089 @default.
• W2214763145 hasConcept C86803240 @default.
• W2214763145 hasConcept C95444343 @default.
• W2214763145 hasConceptScore W2214763145C108625454 @default.
• W2214763145 hasConceptScore W2214763145C134018914 @default.
• W2214763145 hasConceptScore W2214763145C1491633281 @default.
• W2214763145 hasConceptScore W2214763145C153911025 @default.
• W2214763145 hasConceptScore W2214763145C154317977 @default.
• W2214763145 hasConceptScore W2214763145C159047783 @default.
• W2214763145 hasConceptScore W2214763145C202751555 @default.
• W2214763145 hasConceptScore W2214763145C2522874641 @default.
• W2214763145 hasConceptScore W2214763145C2779777497 @default.
• W2214763145 hasConceptScore W2214763145C2780841215 @default.
• W2214763145 hasConceptScore W2214763145C54355233 @default.
• W2214763145 hasConceptScore W2214763145C55493867 @default.
• W2214763145 hasConceptScore W2214763145C73588182 @default.
• W2214763145 hasConceptScore W2214763145C81885089 @default.
• W2214763145 hasConceptScore W2214763145C86803240 @default.
• W2214763145 hasConceptScore W2214763145C95444343 @default.
• W2214763145 hasIssue "2" @default.
• W2214763145 hasLocation W22147631451 @default.
• W2214763145 hasLocation W22147631452 @default.
• W2214763145 hasLocation W22147631453 @default.
• W2214763145 hasOpenAccess W2214763145 @default.
• W2214763145 hasPrimaryLocation W22147631451 @default.
• W2214763145 hasRelatedWork W112407786 @default.
• W2214763145 hasRelatedWork W1968759419 @default.
• W2214763145 hasRelatedWork W2044730940 @default.

• next