FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2214929013> ?p ?o ?g. }

• W2214929013 endingPage "516" @default.
• W2214929013 startingPage "509" @default.
• W2214929013 abstract "The aim of this study was to assess the impact of genetic variants of oligoadenylate synthetase 1 (OAS1) single-nucleotide polymorphism (SNP) rs10774671 at the exon 7 splice acceptor site on liver fibrosis progression and hepatitis C virus (HCV) outcome in Egyptian HCV genotype 4 patients. In this study, 195 subjects were enrolled; 60 controls and 135 chronic HCV genotype 4 patients with different fibrosis grades. All subjects were genotyped for OAS1 SNP rs10774671 polymorphism by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) analysis. There was an increasing trend of liver fibrosis progression as 52.9% GG, 73.6% GA, and 83.3% AA genotypes were detected in late fibrosis patients (p = 0.025). The AA genotype was higher in the late fibrosis group than in the early fibrosis group (83.3% vs. 16.7%) (p = 0.001). The A allele was significantly affecting the liver fibrosis progression rate, more than the G allele (p = 0.001). The multivariate analysis showed that the OAS1 GA and AA genotypes were independent factors associated with liver progression (p = 0.009, odds ratio [OR] 3.467, 95% confidence interval [CI] 1.273-7.584). In addition, the A allele was associated with liver fibrosis progression (p = 0.014, OR 2.525, 95% CI 1.157-4.545). The polymorphism at OAS1 exon 7 rs3741981 might be a potential genetic marker and can be useful in the assessment of liver fibrosis progression and disease outcome in HCV-infected patients." @default.
• W2214929013 created "2016-06-24" @default.
• W2214929013 creator A5011043165 @default.
• W2214929013 creator A5020864706 @default.
• W2214929013 creator A5030530898 @default.
• W2214929013 creator A5041416638 @default.
• W2214929013 creator A5052342613 @default.
• W2214929013 creator A5057731496 @default.
• W2214929013 creator A5083887856 @default.
• W2214929013 date "2015-11-01" @default.
• W2214929013 modified "2023-10-05" @default.
• W2214929013 title "Impact of<i>OAS1</i>Exon 7 rs10774671 Genetic Variation on Liver Fibrosis Progression in Egyptian HCV Genotype 4 Patients" @default.
• W2214929013 cites W1240849929 @default.
• W2214929013 cites W1525567098 @default.
• W2214929013 cites W1889110945 @default.
• W2214929013 cites W1966043531 @default.
• W2214929013 cites W1973479681 @default.
• W2214929013 cites W1989653961 @default.
• W2214929013 cites W2004540833 @default.
• W2214929013 cites W2012758910 @default.
• W2214929013 cites W2017013905 @default.
• W2214929013 cites W2028990156 @default.
• W2214929013 cites W2035117693 @default.
• W2214929013 cites W2046352465 @default.
• W2214929013 cites W2055749608 @default.
• W2214929013 cites W2057484128 @default.
• W2214929013 cites W2073727412 @default.
• W2214929013 cites W2086887894 @default.
• W2214929013 cites W2094174828 @default.
• W2214929013 cites W2099336504 @default.
• W2214929013 cites W2104010560 @default.
• W2214929013 cites W2115266735 @default.
• W2214929013 cites W2118682137 @default.
• W2214929013 cites W2122664567 @default.
• W2214929013 cites W2125238675 @default.
• W2214929013 cites W2126413800 @default.
• W2214929013 cites W2126916706 @default.
• W2214929013 cites W2130525876 @default.
• W2214929013 cites W2131329112 @default.
• W2214929013 cites W2147572654 @default.
• W2214929013 cites W2154224440 @default.
• W2214929013 cites W2162447025 @default.
• W2214929013 cites W2164852591 @default.
• W2214929013 cites W2165094405 @default.
• W2214929013 cites W2333452860 @default.
• W2214929013 cites W306366819 @default.
• W2214929013 cites W4245216028 @default.
• W2214929013 doi "https://doi.org/10.1089/vim.2015.0041" @default.
• W2214929013 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26505957" @default.
• W2214929013 hasPublicationYear "2015" @default.
• W2214929013 type Work @default.
• W2214929013 sameAs 2214929013 @default.
• W2214929013 citedByCount "14" @default.
• W2214929013 countsByYear W22149290132016 @default.
• W2214929013 countsByYear W22149290132017 @default.
• W2214929013 countsByYear W22149290132018 @default.
• W2214929013 countsByYear W22149290132019 @default.
• W2214929013 countsByYear W22149290132020 @default.
• W2214929013 countsByYear W22149290132022 @default.
• W2214929013 countsByYear W22149290132023 @default.
• W2214929013 crossrefType "journal-article" @default.
• W2214929013 hasAuthorship W2214929013A5011043165 @default.
• W2214929013 hasAuthorship W2214929013A5020864706 @default.
• W2214929013 hasAuthorship W2214929013A5030530898 @default.
• W2214929013 hasAuthorship W2214929013A5041416638 @default.
• W2214929013 hasAuthorship W2214929013A5052342613 @default.
• W2214929013 hasAuthorship W2214929013A5057731496 @default.
• W2214929013 hasAuthorship W2214929013A5083887856 @default.
• W2214929013 hasConcept C104317684 @default.
• W2214929013 hasConcept C126322002 @default.
• W2214929013 hasConcept C135763542 @default.
• W2214929013 hasConcept C139275648 @default.
• W2214929013 hasConcept C153209595 @default.
• W2214929013 hasConcept C156957248 @default.
• W2214929013 hasConcept C168007829 @default.
• W2214929013 hasConcept C180754005 @default.
• W2214929013 hasConcept C203014093 @default.
• W2214929013 hasConcept C2522874641 @default.
• W2214929013 hasConcept C2776408679 @default.
• W2214929013 hasConcept C2780559512 @default.
• W2214929013 hasConcept C37463918 @default.
• W2214929013 hasConcept C54355233 @default.
• W2214929013 hasConcept C71924100 @default.
• W2214929013 hasConcept C86803240 @default.
• W2214929013 hasConcept C90924648 @default.
• W2214929013 hasConceptScore W2214929013C104317684 @default.
• W2214929013 hasConceptScore W2214929013C126322002 @default.
• W2214929013 hasConceptScore W2214929013C135763542 @default.
• W2214929013 hasConceptScore W2214929013C139275648 @default.
• W2214929013 hasConceptScore W2214929013C153209595 @default.
• W2214929013 hasConceptScore W2214929013C156957248 @default.
• W2214929013 hasConceptScore W2214929013C168007829 @default.
• W2214929013 hasConceptScore W2214929013C180754005 @default.
• W2214929013 hasConceptScore W2214929013C203014093 @default.
• W2214929013 hasConceptScore W2214929013C2522874641 @default.
• W2214929013 hasConceptScore W2214929013C2776408679 @default.
• W2214929013 hasConceptScore W2214929013C2780559512 @default.
• W2214929013 hasConceptScore W2214929013C37463918 @default.

• next