FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2215459356> ?p ?o ?g. }

• W2215459356 endingPage "27" @default.
• W2215459356 startingPage "15" @default.
• W2215459356 abstract "In 1963 Gomatos and Tamm discovered the first natural dsRNA, namely the genomic RNA of reoviruses. A few years later, Lampson et al. (1967) established that dsRNA is the active agent in an extract of a Penicillium funiculosum preparation which, following injection into rabbits, induces interferon (IFN) in serum. They also showed that various natural (i.e. reovirus genomic RNA) or synthetic (i.e. poly rI:rC) dsRNAs induce IFN-α/β in animals and cultured animal cells (Field et al. 1967). These findings support the hypothesis that virus-infected cells stimulate IFN synthesis of surrounding cells by releasing some dsRNA formed during viral replication. Although dsRNAs induce IFN synthesis, several observations show that immunomodulatory and inflammatory activities of dsRNA are achieved through activation of a defined set of genes (O’Malley et al. 1979; Stewart 1979; De Maeyer and De Maeyer-Guignard 1988; Haines et al. 1991). As a consequence, cells synthesize new proteins that change their growth capacity and modulate their functions." @default.
• W2215459356 created "2016-06-24" @default.
• W2215459356 creator A5024383373 @default.
• W2215459356 creator A5035780912 @default.
• W2215459356 creator A5042560289 @default.
• W2215459356 creator A5062786874 @default.
• W2215459356 date "1994-01-01" @default.
• W2215459356 modified "2023-09-27" @default.
• W2215459356 title "Double-Stranded RNAs as Gene Activators" @default.
• W2215459356 cites W1491681156 @default.
• W2215459356 cites W1504251246 @default.
• W2215459356 cites W1533769780 @default.
• W2215459356 cites W1598980789 @default.
• W2215459356 cites W1834094546 @default.
• W2215459356 cites W1964803874 @default.
• W2215459356 cites W1968102722 @default.
• W2215459356 cites W1970023609 @default.
• W2215459356 cites W1979781084 @default.
• W2215459356 cites W1980710496 @default.
• W2215459356 cites W1981509773 @default.
• W2215459356 cites W1987160102 @default.
• W2215459356 cites W1987703174 @default.
• W2215459356 cites W1989212248 @default.
• W2215459356 cites W1994423138 @default.
• W2215459356 cites W2006434949 @default.
• W2215459356 cites W2006558753 @default.
• W2215459356 cites W2012467811 @default.
• W2215459356 cites W2013746487 @default.
• W2215459356 cites W2020611359 @default.
• W2215459356 cites W2024900154 @default.
• W2215459356 cites W2030360697 @default.
• W2215459356 cites W2032538150 @default.
• W2215459356 cites W2053270830 @default.
• W2215459356 cites W2054132042 @default.
• W2215459356 cites W2058885505 @default.
• W2215459356 cites W2059415989 @default.
• W2215459356 cites W2059920805 @default.
• W2215459356 cites W2061932605 @default.
• W2215459356 cites W2064495999 @default.
• W2215459356 cites W2067159438 @default.
• W2215459356 cites W2068270309 @default.
• W2215459356 cites W2068577315 @default.
• W2215459356 cites W2069235651 @default.
• W2215459356 cites W2069659862 @default.
• W2215459356 cites W2075077903 @default.
• W2215459356 cites W2085070717 @default.
• W2215459356 cites W2087174193 @default.
• W2215459356 cites W2100106962 @default.
• W2215459356 cites W2102776981 @default.
• W2215459356 cites W2104808848 @default.
• W2215459356 cites W2110542621 @default.
• W2215459356 cites W2112834292 @default.
• W2215459356 cites W2128432936 @default.
• W2215459356 cites W2141515661 @default.
• W2215459356 cites W2162299766 @default.
• W2215459356 cites W2162810103 @default.
• W2215459356 cites W2163853656 @default.
• W2215459356 cites W2181371415 @default.
• W2215459356 cites W2260773222 @default.
• W2215459356 cites W2314721164 @default.
• W2215459356 cites W2321504916 @default.
• W2215459356 cites W2330526016 @default.
• W2215459356 cites W80158289 @default.
• W2215459356 doi "https://doi.org/10.1007/978-3-642-78549-8_2" @default.
• W2215459356 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8061883" @default.
• W2215459356 hasPublicationYear "1994" @default.
• W2215459356 type Work @default.
• W2215459356 sameAs 2215459356 @default.
• W2215459356 citedByCount "8" @default.
• W2215459356 countsByYear W22154593562012 @default.
• W2215459356 crossrefType "book-chapter" @default.
• W2215459356 hasAuthorship W2215459356A5024383373 @default.
• W2215459356 hasAuthorship W2215459356A5035780912 @default.
• W2215459356 hasAuthorship W2215459356A5042560289 @default.
• W2215459356 hasAuthorship W2215459356A5062786874 @default.
• W2215459356 hasConcept C104317684 @default.
• W2215459356 hasConcept C140704245 @default.
• W2215459356 hasConcept C150194340 @default.
• W2215459356 hasConcept C153911025 @default.
• W2215459356 hasConcept C159047783 @default.
• W2215459356 hasConcept C166703698 @default.
• W2215459356 hasConcept C2191507 @default.
• W2215459356 hasConcept C2522874641 @default.
• W2215459356 hasConcept C2776178377 @default.
• W2215459356 hasConcept C54355233 @default.
• W2215459356 hasConcept C67705224 @default.
• W2215459356 hasConcept C86803240 @default.
• W2215459356 hasConcept C95444343 @default.
• W2215459356 hasConceptScore W2215459356C104317684 @default.
• W2215459356 hasConceptScore W2215459356C140704245 @default.
• W2215459356 hasConceptScore W2215459356C150194340 @default.
• W2215459356 hasConceptScore W2215459356C153911025 @default.
• W2215459356 hasConceptScore W2215459356C159047783 @default.
• W2215459356 hasConceptScore W2215459356C166703698 @default.
• W2215459356 hasConceptScore W2215459356C2191507 @default.
• W2215459356 hasConceptScore W2215459356C2522874641 @default.
• W2215459356 hasConceptScore W2215459356C2776178377 @default.
• W2215459356 hasConceptScore W2215459356C54355233 @default.

• next