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- W2215743582 abstract "Zinc excess and insufficiency can moderate a cascade of metabolic processes that adversely affect the health of human beings and other organisms. Exposure to elevated levels of zinc and zinc-containing compounds can result in a variety of adverse effects in the gastrointestinal, hematological, and respiratory systems along with alterations in the cardiovascular and neurological systems of humans. In spite of the thousands of papers that have been published on biological effects of zinc, the challenge of quantifying the range of exposure doses that constitute zinc deficiency versus excess remains unresolved and some recent studies have pointed to a considerable overlap between what has generally been considered to be the essential dose and toxic dose, suggesting that the dose–response curve for zinc may not be a ‘U’ but a ‘V’. The limited margin of safety should be of some concern since millions of people are currently being exposed to various levels of zinc through food supplements and additives, medicines, disinfectants, antiseptic and deodorant preparations, and dental cement." @default.
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- W2215743582 date "2011-01-01" @default.
- W2215743582 modified "2023-09-25" @default.
- W2215743582 title "Zinc Toxicity in Humans" @default.
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- W2215743582 doi "https://doi.org/10.1016/b978-0-444-52272-6.00675-9" @default.
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