FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2216157069> ?p ?o ?g. }

• W2216157069 endingPage "1603" @default.
• W2216157069 startingPage "1597" @default.
• W2216157069 abstract "Aseptic prosthetic loosening is known to be an inflammatory, cellular process. We hypothesized that the synovial cell count would significantly differ among normal controls, patients with aseptic loosening, and patients with other etiologies of aseptic failure after total knee arthroplasty and thus that the cell count would be useful in the diagnosis of aseptic loosening.Over a six-year time period, all patients undergoing revision total knee arthroplasties at our institution underwent prospective intraoperative aspiration by the two senior authors. Each patient was assigned to a failure category on the basis of a priori criteria: aseptic loosening, periprosthetic infection, component wear, periprosthetic fracture, component malposition, instability, stiffness, and extensor mechanism failure. Simultaneously, patients with well-functioning total knee replacements underwent aspiration as normal controls. Aspirate characteristics were then compared between groups. Receiver-operating characteristic curves were created to determine optimal white blood-cell cutoffs when periprosthetic infection was compared with each individual failure category.Thirty normal control patients and 433 patients who underwent revision total knee arthroplasties were included in this study. The synovial white blood-cell count in the normal control group was 558 ± 522 cells/μL, which did not significantly differ (p = 0.091) from that taken from patients with aseptic loosening (947 ± 1027 cells/μL). However, normal controls had significantly higher white blood-cell counts than subjects with stiffness (367 ± 392 cells/μL; p = 0.002) and significantly lower white blood-cell counts than subjects with periprosthetic fractures (1687 ± 1613 cells/μL; p = 0.002). Subjects with aseptic loosening had significantly higher white blood-cell counts than subjects with component malpositioning (p = 0.002) or stiffness (p = 0.001). When individual aseptic failure categories were compared with periprosthetic infection, the optimal white blood-cell cutoff varied widely, including 2104 cells/μL for component malposition and 4697 cells/μL for periprosthetic fracture, and the optimal differential segmented cell count percentages varied from 47% to 83%.Although synovial fluid aspirates in patients with aseptic loosening and those with normal total knee arthroplasties did not differ, synovial fluid aspirate characteristics differed among categories of aseptic failure. As a result, the optimal diagnosis of periprosthetic infection on the basis of synovial aspiration results may need to utilize different cutoff values depending on the alternative mode of failure being considered. Large prospective studies will be necessary to validate these threshold values." @default.
• W2216157069 created "2016-06-24" @default.
• W2216157069 creator A5029432162 @default.
• W2216157069 creator A5067436657 @default.
• W2216157069 creator A5078606310 @default.
• W2216157069 creator A5086734251 @default.
• W2216157069 date "2015-10-07" @default.
• W2216157069 modified "2023-09-24" @default.
• W2216157069 title "Evaluation of the Role for Synovial Aspiration in the Diagnosis of Aseptic Loosening After Total Knee Arthroplasty" @default.
• W2216157069 cites W1570870078 @default.
• W2216157069 cites W1758276508 @default.
• W2216157069 cites W1782337071 @default.
• W2216157069 cites W1865204542 @default.
• W2216157069 cites W1885826309 @default.
• W2216157069 cites W1974966308 @default.
• W2216157069 cites W1976366703 @default.
• W2216157069 cites W1976862940 @default.
• W2216157069 cites W1999725788 @default.
• W2216157069 cites W2000115593 @default.
• W2216157069 cites W2000445173 @default.
• W2216157069 cites W2012975381 @default.
• W2216157069 cites W2017941924 @default.
• W2216157069 cites W2021264991 @default.
• W2216157069 cites W2037438170 @default.
• W2216157069 cites W2045161690 @default.
• W2216157069 cites W2047435898 @default.
• W2216157069 cites W2065019657 @default.
• W2216157069 cites W2065746442 @default.
• W2216157069 cites W2071500968 @default.
• W2216157069 cites W2086546431 @default.
• W2216157069 cites W2093936699 @default.
• W2216157069 cites W2112524470 @default.
• W2216157069 cites W2129168200 @default.
• W2216157069 cites W2137117175 @default.
• W2216157069 cites W2138023647 @default.
• W2216157069 cites W2145802997 @default.
• W2216157069 cites W2152575748 @default.
• W2216157069 cites W2174712356 @default.
• W2216157069 cites W77939008 @default.
• W2216157069 doi "https://doi.org/10.2106/jbjs.n.01249" @default.
• W2216157069 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26446968" @default.
• W2216157069 hasPublicationYear "2015" @default.
• W2216157069 type Work @default.
• W2216157069 sameAs 2216157069 @default.
• W2216157069 citedByCount "13" @default.
• W2216157069 countsByYear W22161570692016 @default.
• W2216157069 countsByYear W22161570692017 @default.
• W2216157069 countsByYear W22161570692018 @default.
• W2216157069 countsByYear W22161570692019 @default.
• W2216157069 countsByYear W22161570692020 @default.
• W2216157069 countsByYear W22161570692021 @default.
• W2216157069 countsByYear W22161570692022 @default.
• W2216157069 countsByYear W22161570692023 @default.
• W2216157069 crossrefType "journal-article" @default.
• W2216157069 hasAuthorship W2216157069A5029432162 @default.
• W2216157069 hasAuthorship W2216157069A5067436657 @default.
• W2216157069 hasAuthorship W2216157069A5078606310 @default.
• W2216157069 hasAuthorship W2216157069A5086734251 @default.
• W2216157069 hasConcept C126322002 @default.
• W2216157069 hasConcept C141071460 @default.
• W2216157069 hasConcept C142724271 @default.
• W2216157069 hasConcept C181268634 @default.
• W2216157069 hasConcept C188816634 @default.
• W2216157069 hasConcept C204787440 @default.
• W2216157069 hasConcept C2776164576 @default.
• W2216157069 hasConcept C2776268809 @default.
• W2216157069 hasConcept C2778120723 @default.
• W2216157069 hasConcept C2778336525 @default.
• W2216157069 hasConcept C2778488018 @default.
• W2216157069 hasConcept C3017871827 @default.
• W2216157069 hasConcept C71924100 @default.
• W2216157069 hasConceptScore W2216157069C126322002 @default.
• W2216157069 hasConceptScore W2216157069C141071460 @default.
• W2216157069 hasConceptScore W2216157069C142724271 @default.
• W2216157069 hasConceptScore W2216157069C181268634 @default.
• W2216157069 hasConceptScore W2216157069C188816634 @default.
• W2216157069 hasConceptScore W2216157069C204787440 @default.
• W2216157069 hasConceptScore W2216157069C2776164576 @default.
• W2216157069 hasConceptScore W2216157069C2776268809 @default.
• W2216157069 hasConceptScore W2216157069C2778120723 @default.
• W2216157069 hasConceptScore W2216157069C2778336525 @default.
• W2216157069 hasConceptScore W2216157069C2778488018 @default.
• W2216157069 hasConceptScore W2216157069C3017871827 @default.
• W2216157069 hasConceptScore W2216157069C71924100 @default.
• W2216157069 hasIssue "19" @default.
• W2216157069 hasLocation W22161570691 @default.
• W2216157069 hasLocation W22161570692 @default.
• W2216157069 hasOpenAccess W2216157069 @default.
• W2216157069 hasPrimaryLocation W22161570691 @default.
• W2216157069 hasRelatedWork W1975705478 @default.
• W2216157069 hasRelatedWork W2008346357 @default.
• W2216157069 hasRelatedWork W2150056921 @default.
• W2216157069 hasRelatedWork W2332340949 @default.
• W2216157069 hasRelatedWork W2608935923 @default.
• W2216157069 hasRelatedWork W2626355609 @default.
• W2216157069 hasRelatedWork W3174347156 @default.
• W2216157069 hasRelatedWork W4232089354 @default.
• W2216157069 hasRelatedWork W4244126634 @default.

• next