Matches in SemOpenAlex for { <https://semopenalex.org/work/W2216485897> ?p ?o ?g. }
- W2216485897 endingPage "30" @default.
- W2216485897 startingPage "23" @default.
- W2216485897 abstract "Quercetin, one of the most potent flavonol in the family of flavonoids, has been shown to have benefits against diabetes and its complications. In the present study, we investigated effects of quercetin on depression-like behaviours and hypothalamic-pituitary-adrenal (HPA) axis in diabetic rats.Experimental diabetes was induced by using streptozotocin, and either 50 or 100 mg/kg quercetin was intraperitoneally administered for 21 days. Following the last treatment, animals were subjected to the forced swim test, and subsequently, the blood was obtained by cardiac puncture to measure plasma adrenocorticotropic hormone (ACTH) and corticosterone (CORT) levels.A significant increase of the total immobile time, accompanied by a decrease in the immobility latency, which suggests a depressive status, was observed in diabetic animals that was reversed by the treatment of 50 mg/kg quercetin. However, the higher dose of quercetin (100 mg/kg) was ineffective in alleviating depression-like behaviours. The plasma concentrations of ACTH, and total- and free-CORT were not affected by both doses of quercetin.Therefore, we concluded that the antidepressant-like effects of quercetin in diabetes are independent of the HPA axis." @default.
- W2216485897 created "2016-06-24" @default.
- W2216485897 creator A5011932512 @default.
- W2216485897 creator A5019723010 @default.
- W2216485897 creator A5084600243 @default.
- W2216485897 date "2015-08-03" @default.
- W2216485897 modified "2023-09-26" @default.
- W2216485897 title "Antidepressant‐like effects of quercetin in diabetic rats are independent of hypothalamic–pituitary–adrenal axis" @default.
- W2216485897 cites W1608084702 @default.
- W2216485897 cites W1965344560 @default.
- W2216485897 cites W1966700699 @default.
- W2216485897 cites W1967121645 @default.
- W2216485897 cites W1968125027 @default.
- W2216485897 cites W1974409272 @default.
- W2216485897 cites W1975417376 @default.
- W2216485897 cites W1989194280 @default.
- W2216485897 cites W1992144053 @default.
- W2216485897 cites W1995976999 @default.
- W2216485897 cites W1999341490 @default.
- W2216485897 cites W2000118672 @default.
- W2216485897 cites W2006766617 @default.
- W2216485897 cites W2010900435 @default.
- W2216485897 cites W2026210982 @default.
- W2216485897 cites W2036622936 @default.
- W2216485897 cites W2040817682 @default.
- W2216485897 cites W2041093700 @default.
- W2216485897 cites W2042229937 @default.
- W2216485897 cites W2042911859 @default.
- W2216485897 cites W2052547609 @default.
- W2216485897 cites W2052808590 @default.
- W2216485897 cites W2053532176 @default.
- W2216485897 cites W2058537330 @default.
- W2216485897 cites W2058717577 @default.
- W2216485897 cites W2066585001 @default.
- W2216485897 cites W2068528307 @default.
- W2216485897 cites W2072869405 @default.
- W2216485897 cites W2076383234 @default.
- W2216485897 cites W2079369179 @default.
- W2216485897 cites W2081137905 @default.
- W2216485897 cites W2090095746 @default.
- W2216485897 cites W2094775089 @default.
- W2216485897 cites W2096401930 @default.
- W2216485897 cites W2097950056 @default.
- W2216485897 cites W2099497061 @default.
- W2216485897 cites W2104543818 @default.
- W2216485897 cites W2104811266 @default.
- W2216485897 cites W2109223810 @default.
- W2216485897 cites W2113610552 @default.
- W2216485897 cites W2125278030 @default.
- W2216485897 cites W2130198046 @default.
- W2216485897 cites W2131167630 @default.
- W2216485897 cites W2139197405 @default.
- W2216485897 cites W2144085545 @default.
- W2216485897 cites W2157660669 @default.
- W2216485897 cites W2171340584 @default.
- W2216485897 cites W2172018104 @default.
- W2216485897 cites W2335193727 @default.
- W2216485897 doi "https://doi.org/10.1017/neu.2015.45" @default.
- W2216485897 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26234153" @default.
- W2216485897 hasPublicationYear "2015" @default.
- W2216485897 type Work @default.
- W2216485897 sameAs 2216485897 @default.
- W2216485897 citedByCount "33" @default.
- W2216485897 countsByYear W22164858972016 @default.
- W2216485897 countsByYear W22164858972017 @default.
- W2216485897 countsByYear W22164858972018 @default.
- W2216485897 countsByYear W22164858972019 @default.
- W2216485897 countsByYear W22164858972020 @default.
- W2216485897 countsByYear W22164858972021 @default.
- W2216485897 countsByYear W22164858972022 @default.
- W2216485897 countsByYear W22164858972023 @default.
- W2216485897 crossrefType "journal-article" @default.
- W2216485897 hasAuthorship W2216485897A5011932512 @default.
- W2216485897 hasAuthorship W2216485897A5019723010 @default.
- W2216485897 hasAuthorship W2216485897A5084600243 @default.
- W2216485897 hasConcept C126322002 @default.
- W2216485897 hasConcept C134018914 @default.
- W2216485897 hasConcept C185592680 @default.
- W2216485897 hasConcept C2778004101 @default.
- W2216485897 hasConcept C2779146795 @default.
- W2216485897 hasConcept C2779177272 @default.
- W2216485897 hasConcept C2779280383 @default.
- W2216485897 hasConcept C2780352252 @default.
- W2216485897 hasConcept C2780546910 @default.
- W2216485897 hasConcept C2781161787 @default.
- W2216485897 hasConcept C2781263971 @default.
- W2216485897 hasConcept C55493867 @default.
- W2216485897 hasConcept C555293320 @default.
- W2216485897 hasConcept C71315377 @default.
- W2216485897 hasConcept C71924100 @default.
- W2216485897 hasConceptScore W2216485897C126322002 @default.
- W2216485897 hasConceptScore W2216485897C134018914 @default.
- W2216485897 hasConceptScore W2216485897C185592680 @default.
- W2216485897 hasConceptScore W2216485897C2778004101 @default.
- W2216485897 hasConceptScore W2216485897C2779146795 @default.
- W2216485897 hasConceptScore W2216485897C2779177272 @default.
- W2216485897 hasConceptScore W2216485897C2779280383 @default.
- W2216485897 hasConceptScore W2216485897C2780352252 @default.