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• W2216680543 abstract "Insulin resistance with compensatory hyperinsulinemia has been demonstrated to occur in 50–70% of women with polycystic ovary syndrome (PCOS), regardless of weight. Hyperinsulinemia stimulates excess ovarian androgen production, thereby contributing to the hyperandrogenism and chronic anovulation characteristic of PCOS. The exact cause of insulin resistance in PCOS is unknown, but it appears to be related to a postbinding defect in insulin receptor-mediated signal transduction. Because of insulin resistance, women with PCOS are at risk for several long-term metabolic complications, including type 2 diabetes and cardiovascular disease." @default.
• W2216680543 created "2016-06-24" @default.
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• W2216680543 date "2007-11-07" @default.
• W2216680543 modified "2023-09-26" @default.
• W2216680543 title "Insulin Resistance and Hyperinsulinism in the Polycystic Ovary Syndrome" @default.
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• W2216680543 doi "https://doi.org/10.1007/978-1-59745-179-6_24" @default.
• W2216680543 hasPublicationYear "2007" @default.
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