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- W2217080706 abstract "The structural features and dynamics of biological macromolecules underlie the molecular biology and correct functioning of cells. However, heterogeneity and other complexity of these molecules and their interactions often lead to loss of important information in traditional biophysical experiments. Single-molecule methods have dramatically altered the conceptual thinking and experimental tests available for such studies, leveraging their ability to avoid ensemble averaging. Here, I discuss briefly the rise of fluorescence single-molecule methods over the past two decades, a few key applications, and end with a view to challenges and future prospects." @default.
- W2217080706 created "2016-06-24" @default.
- W2217080706 creator A5042463481 @default.
- W2217080706 date "2016-01-01" @default.
- W2217080706 modified "2023-10-12" @default.
- W2217080706 title "Deciphering Complexity in Molecular Biophysics with Single-Molecule Resolution" @default.
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- W2217080706 doi "https://doi.org/10.1016/j.jmb.2015.12.011" @default.
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