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• W2217389800 startingPage "35" @default.
• W2217389800 abstract "Infections of the central nervous system (CNS) with intracellular pathogens are different in many respects from infections in other parts of the body due to both the anatomical and functional properties of the brain and the biological basis of immune surveillance in the CNS. Damage to brain cells might have severe consequences for the entire body and, in many instances, would conceivably interfere with vital functions. The CNS is particularly vulnerable to pathological stimuli since it consists of highly differentiated cell populations with complex functionally integrated cell-to-cell connections and specialised cytoplasmic membranes. Furthermore, CNS tissue is unique in its high metabolic rate and relative lack of capacity to regenerate. While persistent infection by a non-cytopathogenic virus in cells of an organ with a low-energy requirement and a high rate of regeneration may be tolerated, in CNS tissue such infections may interfere with normal function, especially when neurones are affected (Johnson 1982). From this point of view, the paucity of lymphatic drainage and the lack of constitutive expression of immuneregulatory molecules, e.g. MHC class II and even class I, make sense. Fortunately, the participation of the CNS in a viral infection is relatively uncommon, but it may develop as a complication of many systemic viral infections. The special situation in CNS with its quasi-syncytium favours persistent infection without immediate destruction of the infected target cells. In the long run, however, functional deficits, progressive disease and eventually death of the individual ensue." @default.
• W2217389800 created "2016-06-24" @default.
• W2217389800 creator A5088343134 @default.
• W2217389800 date "2001-01-01" @default.
• W2217389800 modified "2023-09-23" @default.
• W2217389800 title "Slow and Persistent Virus Infections of Neurones — A Compromise for Neuronal Survival" @default.
• W2217389800 cites W131624529 @default.
• W2217389800 cites W1496968114 @default.
• W2217389800 cites W1500508298 @default.
• W2217389800 cites W1508312133 @default.
• W2217389800 cites W1508749719 @default.
• W2217389800 cites W1511694450 @default.
• W2217389800 cites W1514436302 @default.
• W2217389800 cites W1521407235 @default.
• W2217389800 cites W1533153884 @default.
• W2217389800 cites W1537701500 @default.
• W2217389800 cites W1548755772 @default.
• W2217389800 cites W1548951258 @default.
• W2217389800 cites W1557586692 @default.
• W2217389800 cites W1558718465 @default.
• W2217389800 cites W1575761699 @default.
• W2217389800 cites W1588993666 @default.
• W2217389800 cites W1591507258 @default.
• W2217389800 cites W1599332920 @default.
• W2217389800 cites W1599718070 @default.
• W2217389800 cites W1603367311 @default.
• W2217389800 cites W1666250310 @default.
• W2217389800 cites W171727220 @default.
• W2217389800 cites W1749381187 @default.
• W2217389800 cites W1756422255 @default.
• W2217389800 cites W176342860 @default.
• W2217389800 cites W1806868798 @default.
• W2217389800 cites W1812049817 @default.
• W2217389800 cites W1817103017 @default.
• W2217389800 cites W1819121222 @default.
• W2217389800 cites W1831468057 @default.
• W2217389800 cites W1845094941 @default.
• W2217389800 cites W1851145629 @default.
• W2217389800 cites W1899341523 @default.
• W2217389800 cites W1900471667 @default.
• W2217389800 cites W1905837770 @default.
• W2217389800 cites W1933419033 @default.
• W2217389800 cites W1944731310 @default.
• W2217389800 cites W1945056250 @default.
• W2217389800 cites W1959096464 @default.
• W2217389800 cites W1966403513 @default.
• W2217389800 cites W1966897067 @default.
• W2217389800 cites W1967080261 @default.
• W2217389800 cites W1970441521 @default.
• W2217389800 cites W1972269235 @default.
• W2217389800 cites W1980477679 @default.
• W2217389800 cites W1980542137 @default.
• W2217389800 cites W1981482118 @default.
• W2217389800 cites W1983114840 @default.
• W2217389800 cites W1985794335 @default.
• W2217389800 cites W1986621976 @default.
• W2217389800 cites W1986719728 @default.
• W2217389800 cites W1987739388 @default.
• W2217389800 cites W1988256009 @default.
• W2217389800 cites W1989634188 @default.
• W2217389800 cites W1989975469 @default.
• W2217389800 cites W1991520979 @default.
• W2217389800 cites W1991536902 @default.
• W2217389800 cites W1997113780 @default.
• W2217389800 cites W1999866182 @default.
• W2217389800 cites W2004670971 @default.
• W2217389800 cites W2004812763 @default.
• W2217389800 cites W2006593236 @default.
• W2217389800 cites W2012601730 @default.
• W2217389800 cites W2012975085 @default.
• W2217389800 cites W2013185599 @default.
• W2217389800 cites W2013851814 @default.
• W2217389800 cites W2014164228 @default.
• W2217389800 cites W2014379195 @default.
• W2217389800 cites W2014571704 @default.
• W2217389800 cites W2015998617 @default.
• W2217389800 cites W2018487380 @default.
• W2217389800 cites W2019442719 @default.
• W2217389800 cites W2021227608 @default.
• W2217389800 cites W2022009363 @default.
• W2217389800 cites W2022340659 @default.
• W2217389800 cites W2022549765 @default.
• W2217389800 cites W2022641006 @default.
• W2217389800 cites W2022942097 @default.
• W2217389800 cites W2027838150 @default.
• W2217389800 cites W2028010502 @default.
• W2217389800 cites W2032348735 @default.
• W2217389800 cites W2035336072 @default.
• W2217389800 cites W2040674541 @default.
• W2217389800 cites W2044126432 @default.
• W2217389800 cites W2045337210 @default.
• W2217389800 cites W2045418112 @default.
• W2217389800 cites W2046341790 @default.
• W2217389800 cites W2048258437 @default.
• W2217389800 cites W2050707975 @default.
• W2217389800 cites W2058423707 @default.
• W2217389800 cites W2060361076 @default.
• W2217389800 cites W2060520834 @default.

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