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• W2217549633 abstract "Relative risk is the epidemiologic measure of risk presented most often to indicate the benefits and hazards of oral contraception. This measure of risk is prone to distortion and, unlike the attributable risk measure, does not indicate the absolute probability of a hazardous or beneficial effect of oral contraception. Estimates of the risk of cardiovascular disease in oral contraceptive users quoted most often are derived from studies that are at least a decade old. Changes in the formulation of oral contraceptives and selection of healthy women for use of such contraceptives have probably reduced these risks, although precise estimates for currently marketed oral contraceptive formulations in women free of cardiovascular risk factors are not available. Even considering the probably inflated estimates of the risk of cardiovascular disease in oral contraceptive users derived from the older British studies, oral contraception compares favorably with such activities as automobile use in women less than age 35. The hazards of everyday living are the most appropriate framework for interpreting the risks of oral contraception.Provision of information about the risks of oral contraceptive (OC) use is important to enable women to make rational decisions about fertility control. However, as this paper shows, defining the risks of current OCs based on epidemiologic studies is a difficult task. The relative risk measure is prone to distortion and, unlike the attributable risk measure, does not indicate the absolute probability of a hazardous or beneficial effect of OCs. Estimates of the risk of cardiovascular disease in OC users are often derived from studies that are at least a decade old. Changes in the composition of OCs over time have complicated assessment of the risks to users. Moreover, increased OC use, superimposed on the reduced prevalence of other cardiovascular risk factors, has implications for risk assessment. It is unlikely that risk estimates for each OC formulation will eer be available. The hazards of everyday living, rather than the chances of dying in childbirth, comprise the most appropriate framework for interpreting the risks of OC use. For women 25-34 years of age, the chances of dying from cardiovascular disease as a result of OC use are less than the probability of dying in a car accident. However, for women aged 45 years or more, especially smokers, the risks of OCs substantially exceed the risks of daily life." @default.
• W2217549633 created "2016-06-24" @default.
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• W2217549633 date "1986-09-01" @default.
• W2217549633 modified "2023-09-23" @default.
• W2217549633 title "Epidemiologic assessment of the risks of oral contraception." @default.
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