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- W2217776472 abstract "SMC/kleisin complexes form elongated annular structures, which are critical for chromosome segregation, genome maintenance, and the regulation of gene expression. We describe marked structural similarities between bacterial and eukaryotic SMC/kleisin partner proteins (designated here as kite proteins for kleisin interacting tandem winged-helix (WH) elements of SMC complexes). Kite proteins are integral parts of all prokaryotic SMC complexes and Smc5/6 but not cohesin and condensin. They are made up of tandem WH domains, form homo- or heterodimers via their amino-terminal WH domain, and they associate with the central part of a kleisin subunit. In placental mammals, the kite subunit NSE3 gave rise to several (>60) kite-related proteins, named MAGE, many of which encode tumor- and testis-specific antigens. Based on architectural rather than sequence similarity, we propose an adapted model for the evolution of the SMC protein complexes and discuss potential functional similarities between bacterial Smc/ScpAB and eukaryotic Smc5/6." @default.
- W2217776472 created "2016-06-24" @default.
- W2217776472 creator A5006655704 @default.
- W2217776472 creator A5007805763 @default.
- W2217776472 date "2015-12-01" @default.
- W2217776472 modified "2023-10-12" @default.
- W2217776472 title "Kite Proteins: a Superfamily of SMC/Kleisin Partners Conserved Across Bacteria, Archaea, and Eukaryotes" @default.
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- W2217776472 cites W1967901659 @default.
- W2217776472 cites W1967904525 @default.
- W2217776472 cites W1970203866 @default.
- W2217776472 cites W1972734459 @default.
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- W2217776472 doi "https://doi.org/10.1016/j.str.2015.10.004" @default.
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