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- W2218183054 endingPage "543" @default.
- W2218183054 startingPage "529" @default.
- W2218183054 abstract "During recurrent staphylococcal infections,Staphylococcus aureususes several strategies to evade detection by the host immune system. In this Review, Schneewind and colleagues describe the staphylococcal factors that manipulate innate and adaptive immune responses through inhibition, modification and phagocyte destruction. Staphylococcus aureus, a bacterial commensal of the human nares and skin, is a frequent cause of soft tissue and bloodstream infections. A hallmark of staphylococcal infections is their frequent recurrence, even when treated with antibiotics and surgical intervention, which demonstrates the bacterium's ability to manipulate innate and adaptive immune responses. In this Review, we highlight how S. aureus virulence factors inhibit complement activation, block and destroy phagocytic cells and modify host B cell and T cell responses, and we discuss how these insights might be useful for the development of novel therapies against infections with antibiotic resistant strains such as methicillin-resistant S. aureus." @default.
- W2218183054 created "2016-06-24" @default.
- W2218183054 creator A5005368537 @default.
- W2218183054 creator A5026630913 @default.
- W2218183054 creator A5083128767 @default.
- W2218183054 creator A5083683183 @default.
- W2218183054 date "2015-08-14" @default.
- W2218183054 modified "2023-10-18" @default.
- W2218183054 title "Staphylococcal manipulation of host immune responses" @default.
- W2218183054 cites W1506145586 @default.
- W2218183054 cites W1513423708 @default.
- W2218183054 cites W1540464676 @default.
- W2218183054 cites W1606415723 @default.
- W2218183054 cites W1624721229 @default.
- W2218183054 cites W1625034136 @default.
- W2218183054 cites W1695644463 @default.
- W2218183054 cites W1824328278 @default.
- W2218183054 cites W1873518711 @default.
- W2218183054 cites W1896729116 @default.
- W2218183054 cites W1934585871 @default.
- W2218183054 cites W1944603902 @default.
- W2218183054 cites W1952842430 @default.
- W2218183054 cites W1958470604 @default.
- W2218183054 cites W1963492926 @default.
- W2218183054 cites W1963589824 @default.
- W2218183054 cites W1964621887 @default.
- W2218183054 cites W1964727305 @default.
- W2218183054 cites W1971414899 @default.
- W2218183054 cites W1972791698 @default.
- W2218183054 cites W1973675012 @default.
- W2218183054 cites W1973859476 @default.
- W2218183054 cites W1973944724 @default.
- W2218183054 cites W1973976196 @default.
- W2218183054 cites W1978443198 @default.
- W2218183054 cites W1979214371 @default.
- W2218183054 cites W1982324424 @default.
- W2218183054 cites W1983302027 @default.
- W2218183054 cites W1986011501 @default.
- W2218183054 cites W1987513560 @default.
- W2218183054 cites W1987855165 @default.
- W2218183054 cites W1989680705 @default.
- W2218183054 cites W1990643927 @default.
- W2218183054 cites W1991532243 @default.
- W2218183054 cites W1992434978 @default.
- W2218183054 cites W1994753721 @default.
- W2218183054 cites W1996486159 @default.
- W2218183054 cites W2000636931 @default.
- W2218183054 cites W2001203391 @default.
- W2218183054 cites W2002247748 @default.
- W2218183054 cites W2003086561 @default.
- W2218183054 cites W2009090811 @default.
- W2218183054 cites W2009108165 @default.
- W2218183054 cites W2010717419 @default.
- W2218183054 cites W2011385850 @default.
- W2218183054 cites W2013424910 @default.
- W2218183054 cites W2014377287 @default.
- W2218183054 cites W2021096750 @default.
- W2218183054 cites W2023775210 @default.
- W2218183054 cites W2027988203 @default.
- W2218183054 cites W2029099352 @default.
- W2218183054 cites W2030407623 @default.
- W2218183054 cites W2031317540 @default.
- W2218183054 cites W2031438130 @default.
- W2218183054 cites W2032802820 @default.
- W2218183054 cites W2036103344 @default.
- W2218183054 cites W2036177806 @default.
- W2218183054 cites W2037341401 @default.
- W2218183054 cites W2037679972 @default.
- W2218183054 cites W2039617999 @default.
- W2218183054 cites W2042645266 @default.
- W2218183054 cites W2044750677 @default.
- W2218183054 cites W2048580389 @default.
- W2218183054 cites W2052831663 @default.
- W2218183054 cites W2056666597 @default.
- W2218183054 cites W2057387605 @default.
- W2218183054 cites W2062083443 @default.
- W2218183054 cites W2063253081 @default.
- W2218183054 cites W2063966020 @default.
- W2218183054 cites W2064648061 @default.
- W2218183054 cites W2068041880 @default.
- W2218183054 cites W2068396700 @default.
- W2218183054 cites W2069608343 @default.
- W2218183054 cites W2069699883 @default.
- W2218183054 cites W2075601288 @default.
- W2218183054 cites W2076389024 @default.
- W2218183054 cites W2084046310 @default.
- W2218183054 cites W2084409051 @default.
- W2218183054 cites W2084491265 @default.
- W2218183054 cites W2084502463 @default.
- W2218183054 cites W2084871121 @default.
- W2218183054 cites W2086165685 @default.
- W2218183054 cites W2089957746 @default.
- W2218183054 cites W2090544282 @default.
- W2218183054 cites W2092471071 @default.
- W2218183054 cites W2094578161 @default.
- W2218183054 cites W2099361127 @default.
- W2218183054 cites W2099936473 @default.
- W2218183054 cites W2100783252 @default.