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• W2219055154 abstract "The article on the evaluation of the effectiveness of mature red cell and reticulocyte parameters under three conditions: iron deficiency anemia, anemia of chronic disease (ACD), and anemia of chronic disease associated with absolute iron deficiency by Torino et al.1 is very valuable. Automated reticulocyte counts are widely used in the clinical laboratory due to their greater precision, accuracy and reproducibility compared to those obtained using the microscope. The most important benefit of automated methods is the greater precision of counts. By analyzing a much greater number of reticulocytes (more than ten thousand), the statistical error is minimized.2 Visual microscopy is still recommended as the comparability method for reticulocytes, despite studies showing that the variation coefficient (VC) ranges from 20% to 40%. Fully automated methods have eliminated inter-observer variability and subjectivity and substantially reduced turnaround time. Automated methods employ a wide variety of reagents for reticulocyte RNA and these show different sensitivity on binding to RNA.3 Therefore, although automated flow cytometric analysis has led to a significant advance in reticulocyte counting, some limitations still persist in comparability across different laboratories" @default.
• W2219055154 created "2016-06-24" @default.
• W2219055154 creator A5068555821 @default.
• W2219055154 date "2015-03-01" @default.
• W2219055154 modified "2023-09-23" @default.
• W2219055154 title "Comment on: Evaluation of erythrocyte and reticulocyte parameters as indicative of iron deficiency in patients with anemia of chronic disease" @default.
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• W2219055154 doi "https://doi.org/10.1016/j.bjhh.2015.02.005" @default.
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