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- W2220222468 abstract "Publisher Summary The chapter reviews in vitro culture of tissues and cells from the alimentary tract. In alimentary tract organs, mesenchymal cells are abundant and are intimately associated with epithelial cells. The epithelial cell populations lining the stomach, small intestine, and colon are extremely heterogeneous, ranging from rapidly renewing undifferentiated cells to highly differentiated cells including the absorptive cells and the secretory cells in the glands of the gastric mucosa and in the intestinal crypts. The optimal requirements for in vitro maintenance and growth of these various cell types that populate the epithelial lining of the stomach and intestine thus differ substantively. Explants of gastric, small intestinal and colonic mucosa can now be maintained consistently in vitro for 24 to 48 hours with minimal alteration of morphology and continued activity of most functional parameters assessed to date. A wide range of short-term studies of gastric and intestinal mucosal function and metabolism now seem possible." @default.
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- W2220222468 title "Chapter 24 Overview" @default.
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