Matches in SemOpenAlex for { <https://semopenalex.org/work/W2221578431> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W2221578431 endingPage "1406" @default.
- W2221578431 startingPage "1397" @default.
- W2221578431 abstract "We aimed to develop a decision aid that estimates whether treatment of latent tuberculosis infection (LTBI) is likely to have a net gain in quality-adjusted life-years for an individual. A Markov model was developed which incorporated personalised estimates for risk of tuberculosis (TB) reactivation, TB death, quality-of-life impairments and treatment side-effects. The net effect of LTBI treatment was quantified in terms of quality-adjusted life-years gained or lost. Analyses were conducted for a representative set of hypothetical patients. LTBI treatment was estimated to be beneficial when the annual risk of TB reactivation exceeded 13/100 000 to 93/100 000 for females aged 10–75 years and 15/100 000 to 119/100 000 for males aged 10–75 years; the numbers needed to treat to avoid one case of TB were 93, 77, 85 and 72, respectively, at these threshold levels. LTBI treatment was estimated to confer a positive net benefit across a broad range of patients with characteristics typically seen in a low incidence setting for TB. Use of the decision aid has the potential to facilitate and increase confidence with LTBI treatment decisions by providing clinicians and patients with personalised estimates of likely net benefit." @default.
- W2221578431 created "2016-06-24" @default.
- W2221578431 creator A5039913549 @default.
- W2221578431 creator A5086460858 @default.
- W2221578431 creator A5090830207 @default.
- W2221578431 date "2015-09-24" @default.
- W2221578431 modified "2023-10-17" @default.
- W2221578431 title "Benefit of treatment of latent tuberculosis infection in individual patients" @default.
- W2221578431 cites W1982348729 @default.
- W2221578431 cites W1994471959 @default.
- W2221578431 cites W2000537504 @default.
- W2221578431 cites W2005972235 @default.
- W2221578431 cites W2013962941 @default.
- W2221578431 cites W2023940135 @default.
- W2221578431 cites W2030772677 @default.
- W2221578431 cites W2071209213 @default.
- W2221578431 cites W2073179098 @default.
- W2221578431 cites W2077268402 @default.
- W2221578431 cites W2089215904 @default.
- W2221578431 cites W2100306921 @default.
- W2221578431 cites W2109182328 @default.
- W2221578431 cites W2110241349 @default.
- W2221578431 cites W2116048433 @default.
- W2221578431 cites W2118322498 @default.
- W2221578431 cites W2121504031 @default.
- W2221578431 cites W2124130461 @default.
- W2221578431 cites W2139663660 @default.
- W2221578431 cites W2148232746 @default.
- W2221578431 cites W2160175710 @default.
- W2221578431 cites W2166431817 @default.
- W2221578431 cites W2168902801 @default.
- W2221578431 doi "https://doi.org/10.1183/13993003.00577-2015" @default.
- W2221578431 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27132273" @default.
- W2221578431 hasPublicationYear "2015" @default.
- W2221578431 type Work @default.
- W2221578431 sameAs 2221578431 @default.
- W2221578431 citedByCount "25" @default.
- W2221578431 countsByYear W22215784312016 @default.
- W2221578431 countsByYear W22215784312017 @default.
- W2221578431 countsByYear W22215784312018 @default.
- W2221578431 countsByYear W22215784312019 @default.
- W2221578431 countsByYear W22215784312020 @default.
- W2221578431 countsByYear W22215784312021 @default.
- W2221578431 countsByYear W22215784312022 @default.
- W2221578431 countsByYear W22215784312023 @default.
- W2221578431 crossrefType "journal-article" @default.
- W2221578431 hasAuthorship W2221578431A5039913549 @default.
- W2221578431 hasAuthorship W2221578431A5086460858 @default.
- W2221578431 hasAuthorship W2221578431A5090830207 @default.
- W2221578431 hasBestOaLocation W22215784311 @default.
- W2221578431 hasConcept C120665830 @default.
- W2221578431 hasConcept C121332964 @default.
- W2221578431 hasConcept C126322002 @default.
- W2221578431 hasConcept C142724271 @default.
- W2221578431 hasConcept C159110408 @default.
- W2221578431 hasConcept C177713679 @default.
- W2221578431 hasConcept C2777975735 @default.
- W2221578431 hasConcept C2779806340 @default.
- W2221578431 hasConcept C2779951463 @default.
- W2221578431 hasConcept C2781069245 @default.
- W2221578431 hasConcept C44249647 @default.
- W2221578431 hasConcept C61511704 @default.
- W2221578431 hasConcept C71924100 @default.
- W2221578431 hasConceptScore W2221578431C120665830 @default.
- W2221578431 hasConceptScore W2221578431C121332964 @default.
- W2221578431 hasConceptScore W2221578431C126322002 @default.
- W2221578431 hasConceptScore W2221578431C142724271 @default.
- W2221578431 hasConceptScore W2221578431C159110408 @default.
- W2221578431 hasConceptScore W2221578431C177713679 @default.
- W2221578431 hasConceptScore W2221578431C2777975735 @default.
- W2221578431 hasConceptScore W2221578431C2779806340 @default.
- W2221578431 hasConceptScore W2221578431C2779951463 @default.
- W2221578431 hasConceptScore W2221578431C2781069245 @default.
- W2221578431 hasConceptScore W2221578431C44249647 @default.
- W2221578431 hasConceptScore W2221578431C61511704 @default.
- W2221578431 hasConceptScore W2221578431C71924100 @default.
- W2221578431 hasIssue "5" @default.
- W2221578431 hasLocation W22215784311 @default.
- W2221578431 hasLocation W22215784312 @default.
- W2221578431 hasOpenAccess W2221578431 @default.
- W2221578431 hasPrimaryLocation W22215784311 @default.
- W2221578431 hasRelatedWork W1955737261 @default.
- W2221578431 hasRelatedWork W2051276691 @default.
- W2221578431 hasRelatedWork W2123708792 @default.
- W2221578431 hasRelatedWork W2412323770 @default.
- W2221578431 hasRelatedWork W2806061655 @default.
- W2221578431 hasRelatedWork W2956144804 @default.
- W2221578431 hasRelatedWork W3036655379 @default.
- W2221578431 hasRelatedWork W3200000059 @default.
- W2221578431 hasRelatedWork W4298140190 @default.
- W2221578431 hasRelatedWork W747133875 @default.
- W2221578431 hasVolume "46" @default.
- W2221578431 isParatext "false" @default.
- W2221578431 isRetracted "false" @default.
- W2221578431 magId "2221578431" @default.
- W2221578431 workType "article" @default.