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- W222178839 abstract "The epidemiological profile, clinical and therapeutic aspects with analysis of prognostic factors of invasive cervical cancer have been studied in a retrospective study on 96 patients in the Farhat Hached University Hospital Centre of Sousse between 1992 and 2000. Cervical cancer is the second genital cancer of women after breast cancer in the tunisian center. The median age was 54 years with 12.5% of women younger than 40 years. The average consultation period was 6.5 months and 20% of the patients consulted 12 months after the beginning of symptomatology. Median tumor size was 4.25 cm and in 70% of cases it was superior than 4 cm. The clinical staging based on the examination under general anaesthesia showed a proportion of 56.3% of inoperable evaluated forms. The histological study revealed a predominance of squamous cell carcinomas (95%) by report to adenocarcinomas (5%). Sixty-six patients (69% of patients) had a complete treatment and were evaluated on the therapeutic plan. The therapeutic strategy was based on radiochirurgical combination for limited stages (56% of patients) and on exclusive radiotherapy for advanced stages (44% of patients). Complete remission after the treatment was obtained in 88% of cases. The overall survival and the event-free survival at 5 years were respectively 80.5 and 75%. Eleven loco-regional recurrences and 5 metastases appeared in the course of follow-up. All the metastases and near 2/3 of recurrences were noted during the first two years of follow-up. The average follow-up was 36 months (extremes: 4–84 months). In an univariable study, factors that had a pejorative impact on the prognosis were—the young age, the clinical advanced stage and the lymph node involvement. Results were better for small size tumors and differentiated tumors but the difference was not significant." @default.
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- W222178839 date "2004-11-01" @default.
- W222178839 modified "2023-09-26" @default.
- W222178839 title "Le cancer invasif du col ut�rin dans le centre tunisien. Approches �pid�miologique, clinique et th�rapeutique. �tude r�trospective de 96 cas" @default.
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- W222178839 doi "https://doi.org/10.1007/s10269-004-0117-5" @default.
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