Matches in SemOpenAlex for { <https://semopenalex.org/work/W2222077434> ?p ?o ?g. }
Showing items 1 to 88 of
88
with 100 items per page.
- W2222077434 endingPage "H1597" @default.
- W2222077434 startingPage "H1589" @default.
- W2222077434 abstract "A low concentration of hyaluronan (HA) in lymph compared with tissue suggests a large bound fraction. To investigate the distribution and mobility of HA and serum albumin (Alb), we eluted the rat tail tendon with a series of l5 successive centrifugations, each preceded by the addition of 0.15 M NaCl (15% of initial wet wt). The eluate concentration fell exponentially versus the accumulated eluate, allowing estimation of the maximal elutable amount (E(HA) and E(Alb)). Alb elution was practically complete from a space of approximately 28% of wet wt at all centrifugation rates. Twenty percent of HA was elutable at 500 rpm, apparently from the same space as Alb, increasing to 40% at >4,000 rpm. This pattern was not significantly influenced by using 2 M NaCl or by the addition of plasma or metabolic inhibitors. Without prehydration and centrifugation at high revolutions per minute, both Alb and HA concentrations fell rapidly toward zero, presumably in part reflecting mobilization of HA- and Alb-free fluid from the collagen intrafibrillar space (3). We conclude that with prehydration the fibrils swell, increasing the intramolecular spaces to become penetrable to HA and allowing removal of HA-containing fluid when the fibrils are compressed by the next centrifugation at high revolutions per minute, increasing E(HA) from 23 to 45%. Chemical binding presumably explains the unelutable 55% of tendon HA. Intrafibrillar HA may act to stabilize the fibrillar volume." @default.
- W2222077434 created "2016-06-24" @default.
- W2222077434 creator A5002944119 @default.
- W2222077434 creator A5046802432 @default.
- W2222077434 creator A5066706316 @default.
- W2222077434 date "2001-10-01" @default.
- W2222077434 modified "2023-10-16" @default.
- W2222077434 title "Distribution spaces for hyaluronan and albumin in rat tail tendons" @default.
- W2222077434 cites W125147743 @default.
- W2222077434 cites W1485530300 @default.
- W2222077434 cites W1783092495 @default.
- W2222077434 cites W1964116173 @default.
- W2222077434 cites W1975413941 @default.
- W2222077434 cites W1981039285 @default.
- W2222077434 cites W1989980757 @default.
- W2222077434 cites W2002343714 @default.
- W2222077434 cites W2010518235 @default.
- W2222077434 cites W2034275429 @default.
- W2222077434 cites W2047346625 @default.
- W2222077434 cites W2050592185 @default.
- W2222077434 cites W2057807180 @default.
- W2222077434 cites W2059013047 @default.
- W2222077434 cites W2059818859 @default.
- W2222077434 cites W2060932633 @default.
- W2222077434 cites W2134263002 @default.
- W2222077434 cites W2148584606 @default.
- W2222077434 cites W2154228555 @default.
- W2222077434 cites W2158473853 @default.
- W2222077434 cites W2159245949 @default.
- W2222077434 cites W2165749967 @default.
- W2222077434 cites W2170326305 @default.
- W2222077434 cites W2234502071 @default.
- W2222077434 cites W2335118956 @default.
- W2222077434 cites W2432209366 @default.
- W2222077434 cites W307590521 @default.
- W2222077434 cites W96119417 @default.
- W2222077434 doi "https://doi.org/10.1152/ajpheart.2001.281.4.h1589" @default.
- W2222077434 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11557548" @default.
- W2222077434 hasPublicationYear "2001" @default.
- W2222077434 type Work @default.
- W2222077434 sameAs 2222077434 @default.
- W2222077434 citedByCount "4" @default.
- W2222077434 countsByYear W22220774342012 @default.
- W2222077434 countsByYear W22220774342015 @default.
- W2222077434 crossrefType "journal-article" @default.
- W2222077434 hasAuthorship W2222077434A5002944119 @default.
- W2222077434 hasAuthorship W2222077434A5046802432 @default.
- W2222077434 hasAuthorship W2222077434A5066706316 @default.
- W2222077434 hasConcept C12554922 @default.
- W2222077434 hasConcept C185592680 @default.
- W2222077434 hasConcept C2776125364 @default.
- W2222077434 hasConcept C2778476535 @default.
- W2222077434 hasConcept C43617362 @default.
- W2222077434 hasConcept C55493867 @default.
- W2222077434 hasConcept C73826308 @default.
- W2222077434 hasConcept C7623868 @default.
- W2222077434 hasConcept C86803240 @default.
- W2222077434 hasConceptScore W2222077434C12554922 @default.
- W2222077434 hasConceptScore W2222077434C185592680 @default.
- W2222077434 hasConceptScore W2222077434C2776125364 @default.
- W2222077434 hasConceptScore W2222077434C2778476535 @default.
- W2222077434 hasConceptScore W2222077434C43617362 @default.
- W2222077434 hasConceptScore W2222077434C55493867 @default.
- W2222077434 hasConceptScore W2222077434C73826308 @default.
- W2222077434 hasConceptScore W2222077434C7623868 @default.
- W2222077434 hasConceptScore W2222077434C86803240 @default.
- W2222077434 hasIssue "4" @default.
- W2222077434 hasLocation W22220774341 @default.
- W2222077434 hasLocation W22220774342 @default.
- W2222077434 hasOpenAccess W2222077434 @default.
- W2222077434 hasPrimaryLocation W22220774341 @default.
- W2222077434 hasRelatedWork W1583843090 @default.
- W2222077434 hasRelatedWork W1994414231 @default.
- W2222077434 hasRelatedWork W2011388482 @default.
- W2222077434 hasRelatedWork W2033636902 @default.
- W2222077434 hasRelatedWork W2262848750 @default.
- W2222077434 hasRelatedWork W2371520255 @default.
- W2222077434 hasRelatedWork W2416084300 @default.
- W2222077434 hasRelatedWork W2438679974 @default.
- W2222077434 hasRelatedWork W4231299192 @default.
- W2222077434 hasRelatedWork W4240549537 @default.
- W2222077434 hasVolume "281" @default.
- W2222077434 isParatext "false" @default.
- W2222077434 isRetracted "false" @default.
- W2222077434 magId "2222077434" @default.
- W2222077434 workType "article" @default.