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- W2224223012 abstract "Alzheimer's disease (AD) is a neurodegenerative brain disorder associated with relentlessly progressive cognitive impairment and memory loss. AD pathology proceeds for decades before cognitive deficits become clinically apparent, opening a window for preventative therapy. Imbalance of clearance and buildup of amyloid β and phosphorylated tau proteins in the central nervous system is believed to contribute to AD pathogenesis. However, multiple clinical trials of treatments aimed at averting accumulation of these proteins have yielded little success, and there is still no disease-modifying intervention. Here, we discuss current knowledge of AD pathology and treatment with an emphasis on emerging biomarkers and treatment strategies." @default.
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- W2224223012 date "2005-09-01" @default.
- W2224223012 modified "2023-09-25" @default.
- W2224223012 title "Strengthening Families: The Role of Community-Based and Grassroots Organizations" @default.
- W2224223012 doi "https://doi.org/10.18043/ncm.66.5.383" @default.
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