Matches in SemOpenAlex for { <https://semopenalex.org/work/W2224273048> ?p ?o ?g. }
Showing items 1 to 69 of
69
with 100 items per page.
- W2224273048 endingPage "4" @default.
- W2224273048 startingPage "770" @default.
- W2224273048 abstract "To establish an extracorporeal circulation (ECC) rat model, and evaluate the inflammatory response and organ injury induced in the model.SD rats were anesthetized and cannulated from right common carotid artery to left femoral vein to establish the bypass of extracorporeal circulation. Then the rats were randomly divided into ECC group and sham group. The rats in ECC group were subjected to extracorporeal circulation for 2 hours and then rest for 2 hours, while the rats in sham group were only observed for 4 hours without extracorporeal circulation. After that, blood routine examination, blood gas analysis, the measurement of pro-inflammatory factors in bronchoalveolar lavage fluid and lung tissue were performed to evaluate the lung injury induced by ECC. Circulating endothelial cells were also calculated by flow cytometry to assess the vascular endothelial injury.At 2 hours after ECC, red blood cell counts in both groups kept normal, while leukocyte and neutrophil counts, plasmatic tumor necrosis factor-a level and neutrophil elastase level, circulating endothelial cells in the rats of ECC group were significantly higher than those in sham group. Tumor necrosis factor-alpha in bronchoalveolar lavage fluid and water content in lung of the ECC rats were also significantly higher, while the oxygenation index was significantly lower. Neutrophil infiltration was also observed in lung tissues with increased thickness of alveolar membrane in ECC group.The ECC model established from right common carotid artery to left femoral vein in our study can successfully induce systemic inflammatory response, and acute lung injury associated with inflammation." @default.
- W2224273048 created "2016-06-24" @default.
- W2224273048 creator A5010539533 @default.
- W2224273048 creator A5020860073 @default.
- W2224273048 creator A5040552741 @default.
- W2224273048 creator A5048998252 @default.
- W2224273048 creator A5052910062 @default.
- W2224273048 creator A5060521138 @default.
- W2224273048 creator A5061328071 @default.
- W2224273048 creator A5062637916 @default.
- W2224273048 creator A5074197949 @default.
- W2224273048 date "2012-09-01" @default.
- W2224273048 modified "2023-09-25" @default.
- W2224273048 title "[Establishment and evaluation of extracorporeal circulation model in rats]." @default.
- W2224273048 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23230758" @default.
- W2224273048 hasPublicationYear "2012" @default.
- W2224273048 type Work @default.
- W2224273048 sameAs 2224273048 @default.
- W2224273048 citedByCount "1" @default.
- W2224273048 countsByYear W22242730482023 @default.
- W2224273048 crossrefType "journal-article" @default.
- W2224273048 hasAuthorship W2224273048A5010539533 @default.
- W2224273048 hasAuthorship W2224273048A5020860073 @default.
- W2224273048 hasAuthorship W2224273048A5040552741 @default.
- W2224273048 hasAuthorship W2224273048A5048998252 @default.
- W2224273048 hasAuthorship W2224273048A5052910062 @default.
- W2224273048 hasAuthorship W2224273048A5060521138 @default.
- W2224273048 hasAuthorship W2224273048A5061328071 @default.
- W2224273048 hasAuthorship W2224273048A5062637916 @default.
- W2224273048 hasAuthorship W2224273048A5074197949 @default.
- W2224273048 hasConcept C126322002 @default.
- W2224273048 hasConcept C142724271 @default.
- W2224273048 hasConcept C2776317360 @default.
- W2224273048 hasConcept C2776914184 @default.
- W2224273048 hasConcept C2777714996 @default.
- W2224273048 hasConcept C2777961210 @default.
- W2224273048 hasConcept C2994232697 @default.
- W2224273048 hasConcept C42219234 @default.
- W2224273048 hasConcept C71924100 @default.
- W2224273048 hasConceptScore W2224273048C126322002 @default.
- W2224273048 hasConceptScore W2224273048C142724271 @default.
- W2224273048 hasConceptScore W2224273048C2776317360 @default.
- W2224273048 hasConceptScore W2224273048C2776914184 @default.
- W2224273048 hasConceptScore W2224273048C2777714996 @default.
- W2224273048 hasConceptScore W2224273048C2777961210 @default.
- W2224273048 hasConceptScore W2224273048C2994232697 @default.
- W2224273048 hasConceptScore W2224273048C42219234 @default.
- W2224273048 hasConceptScore W2224273048C71924100 @default.
- W2224273048 hasIssue "5" @default.
- W2224273048 hasLocation W22242730481 @default.
- W2224273048 hasOpenAccess W2224273048 @default.
- W2224273048 hasPrimaryLocation W22242730481 @default.
- W2224273048 hasRelatedWork W1990355700 @default.
- W2224273048 hasRelatedWork W1993072895 @default.
- W2224273048 hasRelatedWork W2057153092 @default.
- W2224273048 hasRelatedWork W2078962298 @default.
- W2224273048 hasRelatedWork W2082912322 @default.
- W2224273048 hasRelatedWork W2134367992 @default.
- W2224273048 hasRelatedWork W2312011551 @default.
- W2224273048 hasRelatedWork W2357130602 @default.
- W2224273048 hasRelatedWork W2413084395 @default.
- W2224273048 hasRelatedWork W2463225206 @default.
- W2224273048 hasVolume "43" @default.
- W2224273048 isParatext "false" @default.
- W2224273048 isRetracted "false" @default.
- W2224273048 magId "2224273048" @default.
- W2224273048 workType "article" @default.