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• W2224281762 startingPage "1992" @default.
• W2224281762 abstract "Deregulated expression of miRNAs is related to progression and initiation of human cancers. Although miR-495 has identified in various tumors, its expression and function in renal cell carcinoma (RCC) is still unknown. In this study, we found that the expression of miR-495 was downregulated in RCC cell lines and tissues. Ectopic expression of miR-495 induced G0/G1 phase arrest and suppressed cell proliferation and migration in RCC cell lines. We further validated SATB1 was a direct target of miR-495 in RCC. In addition, re-expression of SATB1 reversed the miR-495-induced inhibition of cell proliferation and migration. These data suggest that miR-495 functions as a tumor suppressor and may be a promising therapeutic target in RCC in the future." @default.
• W2224281762 created "2016-06-24" @default.
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• W2224281762 creator A5073501391 @default.
• W2224281762 creator A5075279435 @default.
• W2224281762 creator A5078348692 @default.
• W2224281762 date "2015-01-01" @default.
• W2224281762 modified "2023-10-18" @default.
• W2224281762 title "MicroRNA-495 suppresses human renal cell carcinoma malignancy by targeting SATB1." @default.
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• W2224281762 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4656775" @default.
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• W2224281762 hasPublicationYear "2015" @default.
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