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• W2224656076 endingPage "894" @default.
• W2224656076 startingPage "886" @default.
• W2224656076 abstract "The F-box proteins (FBPs) in esophageal tumorigenesis are pivotal as they govern a broad array of basic physiological responses including cell growth, cell death and DNA damage repair. Esophageal cancer (EC) is a common and highly aggressive cancer worldwide. Aberrant stabilization of crucial proteins participates in esophageal tumorigenesis. Recently, growing evidence has shown that FBPs play a critical role in oncogenesis, invasion, metastasis and prognosis assessment of EC. In this review we summarized published data on the roles of known FBPs, their respective substrates and the key signaling pathways, in the development of EC, aiming to uncover new ways for the rational design of targeted therapies in EC." @default.
• W2224656076 created "2016-06-24" @default.
• W2224656076 creator A5011236043 @default.
• W2224656076 creator A5015531883 @default.
• W2224656076 creator A5073099217 @default.
• W2224656076 date "2016-01-05" @default.
• W2224656076 modified "2023-10-02" @default.
• W2224656076 title "Involvement of F-box proteins in esophageal cancer (Review)" @default.
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