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- W2224747098 abstract "Hurler syndrome is the most severe form of mucopolysaccharidosis (MPS) Type 1. Progressive neurocognitive decline in this condition can be accompanied by macrocephaly, ventriculomegaly, and/or periventricular signal changes on MRI, which often leads to a neurosurgical referral. In this case, the authors describe a 2-year-old boy with ventriculomegaly and periventricular T2 signal changes, both of which decreased following medical management of Hurler syndrome. The authors discuss the possible mechanisms for this finding and the implications for neurosurgical treatment of this condition." @default.
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- W2224747098 date "2016-05-01" @default.
- W2224747098 modified "2023-09-27" @default.
- W2224747098 title "Regression of ventriculomegaly following medical management of a patient with Hurler syndrome" @default.
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- W2224747098 doi "https://doi.org/10.3171/2015.9.peds15477" @default.
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