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- W2225114903 abstract "The ‘saturation-tension’ curve relating O2 saturation to alveolar Po2, previously described by us for evaluation of venous admixture and diffusion difficulty in the lung, was quantitatively studied in dogs with right-left anatomical shunts prepared by anastomosing pulmonary artery and vein following pneumonectomy. This curve, obtained by oximeter, end-tidal sampler and O2 analyzer, rises in essentially linear fashion at high O2 tensions, both for arterial and for mixed venous blood. When saturation of arterial blood is replotted against alveolar minus arterial O2 tension, the resulting curve is truly linear at high O2 tensions. This was indicated by a theoretical expression derived from the so-called mixing equation for calculating fraction of shunting. The latter may alternatively be calculated using an extrapolation procedure based on the above equation, which was also used to construct theoretical saturation-tension curves for various fractions of shunting. These curves indicate the quantity of O2 carried by hemoglobin, with anatomical shunting and also without. Saturation-tension curves may therefore be used for diagnosing right-left anatomical shunts in patients, as proven in several cases, without recourse to blood samples. Submitted on August 5, 1957" @default.
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- W2225114903 date "1958-01-01" @default.
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- W2225114903 title "Arterial Oxygen Saturation vs. Alveolar Oxygen Tension in Anatomical Venous-Arterial Shunting" @default.
- W2225114903 doi "https://doi.org/10.1152/jappl.1958.12.1.71" @default.
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