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- W2225444375 abstract "It has been estimated that in 1998, physicians will have diagnosed prostate cancer in approximately 200,000 American men, who will be offered a variety of treatments to cure or control the progression of their disease. The lack of data from large, randomized trials with long-term follow-up has caused considerable controversy and confusion regarding the treatment options of newly diagnosed localized prostate cancer. In the absence of such controlled trials, it becomes difficult to compare treatment outcomes because of differing pretreatment risk characteristics and different specific therapeutic techniques. Adding to the confusion are the various endpoints used to gauge the success or failure of a particular treatment. Many prostatectomy and radiation therapy series use prostate-specific antigen (PSA) recurrence-free survival, defined a variety of ways, as an outcome parameter that may not translate into overall and prostate-cancer specific survival within the lifetime of a patient. Also, because of the profound downward-stage migration to more organ-confined disease during the PSA-screened era, improved outcomes reported from recent prostatectomy, external-beam radiation therapy, and interstitial brachytherapy series may not be related only to improvements in specific therapeutic techniques." @default.
- W2225444375 created "2016-06-24" @default.
- W2225444375 creator A5000349193 @default.
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- W2225444375 date "2001-01-01" @default.
- W2225444375 modified "2023-10-16" @default.
- W2225444375 title "Selecting and Counseling Patients on Appropriate Treatment of Prostate Cancer" @default.
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- W2225444375 doi "https://doi.org/10.1007/978-1-59259-010-0_22" @default.
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