Matches in SemOpenAlex for { <https://semopenalex.org/work/W2225612558> ?p ?o ?g. }
- W2225612558 endingPage "54" @default.
- W2225612558 startingPage "43" @default.
- W2225612558 abstract "Background: In utero exposure to xenostrogens may modify the epigenome. We explored the association of prenatal exposure to mixtures of xenoestrogens and genome-wide placental DNA methylation. Materials & methods: Sex-specific associations between methylation changes in placental DNA by doubling the concentration of TEXB-alpha exposure were evaluated by robust multiple linear regression. Two CpG sites were selected for validation and replication in additional male born placentas. Results: No significant associations were found, although the top significant CpGs in boys were located in the LRPAP1, HAGH, PPARGC1B, KCNQ1 and KCNQ1DN genes, previously associated to birth weight, Type 2 diabetes, obesity or steroid hormone signaling. Neither technical validation nor biological replication of the results was found in boys for LRPAP and PPARGC1B. Conclusion: Some suggestive genes were differentially methylated in boys in relation to prenatal xenoestrogen exposure, but our initial findings could not be validated or replicated." @default.
- W2225612558 created "2016-06-24" @default.
- W2225612558 creator A5002857362 @default.
- W2225612558 creator A5006830779 @default.
- W2225612558 creator A5007836073 @default.
- W2225612558 creator A5010088725 @default.
- W2225612558 creator A5023941814 @default.
- W2225612558 creator A5025979260 @default.
- W2225612558 creator A5031153935 @default.
- W2225612558 creator A5040279141 @default.
- W2225612558 creator A5041531004 @default.
- W2225612558 creator A5046359435 @default.
- W2225612558 creator A5050226882 @default.
- W2225612558 creator A5050917806 @default.
- W2225612558 creator A5052680269 @default.
- W2225612558 creator A5064690695 @default.
- W2225612558 creator A5070275885 @default.
- W2225612558 creator A5074377095 @default.
- W2225612558 creator A5075236220 @default.
- W2225612558 creator A5082545896 @default.
- W2225612558 date "2016-01-01" @default.
- W2225612558 modified "2023-10-18" @default.
- W2225612558 title "Prenatal exposure to mixtures of xenoestrogens and genome-wide DNA methylation in human placenta" @default.
- W2225612558 cites W1728636464 @default.
- W2225612558 cites W1909375041 @default.
- W2225612558 cites W1969237332 @default.
- W2225612558 cites W1974562202 @default.
- W2225612558 cites W1975528145 @default.
- W2225612558 cites W1976342911 @default.
- W2225612558 cites W1980129249 @default.
- W2225612558 cites W1982810690 @default.
- W2225612558 cites W1986684176 @default.
- W2225612558 cites W1990924578 @default.
- W2225612558 cites W1992892752 @default.
- W2225612558 cites W1993210636 @default.
- W2225612558 cites W1994194752 @default.
- W2225612558 cites W2004599580 @default.
- W2225612558 cites W2005529814 @default.
- W2225612558 cites W2006770045 @default.
- W2225612558 cites W2007203150 @default.
- W2225612558 cites W2009687868 @default.
- W2225612558 cites W2018826413 @default.
- W2225612558 cites W2023939604 @default.
- W2225612558 cites W2024828882 @default.
- W2225612558 cites W2033728890 @default.
- W2225612558 cites W2035392558 @default.
- W2225612558 cites W2037510660 @default.
- W2225612558 cites W2048581231 @default.
- W2225612558 cites W2048655519 @default.
- W2225612558 cites W2049422251 @default.
- W2225612558 cites W2049481764 @default.
- W2225612558 cites W2063094219 @default.
- W2225612558 cites W2065408367 @default.
- W2225612558 cites W2067045823 @default.
- W2225612558 cites W2069777680 @default.
- W2225612558 cites W2071764836 @default.
- W2225612558 cites W2072541918 @default.
- W2225612558 cites W2074305712 @default.
- W2225612558 cites W2075829690 @default.
- W2225612558 cites W2076600548 @default.
- W2225612558 cites W2078036688 @default.
- W2225612558 cites W2078059617 @default.
- W2225612558 cites W2081945059 @default.
- W2225612558 cites W2082581058 @default.
- W2225612558 cites W2084007373 @default.
- W2225612558 cites W2087008478 @default.
- W2225612558 cites W2087175878 @default.
- W2225612558 cites W2093056723 @default.
- W2225612558 cites W2095975057 @default.
- W2225612558 cites W2097531668 @default.
- W2225612558 cites W2102222597 @default.
- W2225612558 cites W2108165606 @default.
- W2225612558 cites W2108415927 @default.
- W2225612558 cites W2113305633 @default.
- W2225612558 cites W2117121254 @default.
- W2225612558 cites W2118057169 @default.
- W2225612558 cites W2119883345 @default.
- W2225612558 cites W2120106657 @default.
- W2225612558 cites W2121303247 @default.
- W2225612558 cites W2124853405 @default.
- W2225612558 cites W2128016314 @default.
- W2225612558 cites W2133822216 @default.
- W2225612558 cites W2134682046 @default.
- W2225612558 cites W2140008210 @default.
- W2225612558 cites W2140321480 @default.
- W2225612558 cites W2141956604 @default.
- W2225612558 cites W2142997651 @default.
- W2225612558 cites W2148306389 @default.
- W2225612558 cites W2152603020 @default.
- W2225612558 cites W2155292213 @default.
- W2225612558 cites W2155877766 @default.
- W2225612558 cites W2165700542 @default.
- W2225612558 cites W2170028368 @default.
- W2225612558 cites W2171856214 @default.
- W2225612558 cites W2326800662 @default.
- W2225612558 cites W2918064359 @default.
- W2225612558 doi "https://doi.org/10.2217/epi.15.91" @default.
- W2225612558 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26679211" @default.