Matches in SemOpenAlex for { <https://semopenalex.org/work/W2225746578> ?p ?o ?g. }
- W2225746578 endingPage "6" @default.
- W2225746578 startingPage "6" @default.
- W2225746578 abstract "Mushrooms have been valued for their nutritive content and as traditional medicines; several important medicinal properties of mushrooms have been recognized worldwide.The purpose of this study was to elucidate the cell growth inhibitory potential of four edible mushrooms; Coprinus comatus (O.F. Mull.) Pers. (Agaricaceae), Tricholoma fracticum (Britzelm.) Kreisel (Tricholomataceae), Rhizopogon luteolus Fr. and Nordholm (Rhizopogonaceae), Lentinus tigrinus (Bull.) Fr. (Polyporaceae) on hepatocellular carcinoma (HepG2) cells in conjunction with their antioxidant and antibacterial capacities.Five different extracts of edible mushrooms were obtained using water, methanol, acetone, n-hexane and chloroform as solvent systems for cytotoxic, antioxidant and antibacterial properties.C. comatus showed substantial in vitro cytotoxic activity against HepG2 cell lines with all extracts especially with chloroform 50% inhibition (IC50 value of 0.086 mg/ml) and acetone (IC50 value of 0.420 mg/ml). Chloroform extract of C. comatus had maximum amount of β-carotene (25.94 μg/mg), total phenolic content (76.32 μg/mg) and lycopene (12.00 μg/mg), and n-hexane extract of L. tigrinus had maximum amount of flavonoid (3.67 μg/mg). While chloroform extract of C. comatus showed the highest 2, 2-diphenyl-1-picrylhydrazyl (DPPH) capturing activity (1.579 mg/ml), the best result for metal chelating activity was obtained from methanolic extract (0.842 mg/ml). Moreover, all tested mushrooms demonstrated antibacterial activity and n-hexane extract of L. tigrinus and acetone extracts of T. fracticum were the most active against tested microorganism.These results indicate that different extracts of investigated mushroom have considerable cytotoxic, antioxidant and antibacterial properties and may be utilized as a promising source of therapeutics." @default.
- W2225746578 created "2016-06-24" @default.
- W2225746578 creator A5003114465 @default.
- W2225746578 creator A5030284617 @default.
- W2225746578 creator A5068867176 @default.
- W2225746578 creator A5070047751 @default.
- W2225746578 creator A5072357794 @default.
- W2225746578 creator A5084171007 @default.
- W2225746578 date "2015-01-01" @default.
- W2225746578 modified "2023-10-09" @default.
- W2225746578 title "Cytotoxicity of some edible mushrooms extracts over liver hepatocellular carcinoma cells in conjunction with their antioxidant and antibacterial properties" @default.
- W2225746578 cites W1481401799 @default.
- W2225746578 cites W1823916924 @default.
- W2225746578 cites W1966937062 @default.
- W2225746578 cites W1968164214 @default.
- W2225746578 cites W1970928854 @default.
- W2225746578 cites W1979919435 @default.
- W2225746578 cites W1985634430 @default.
- W2225746578 cites W1986101868 @default.
- W2225746578 cites W1991359041 @default.
- W2225746578 cites W2011638547 @default.
- W2225746578 cites W2015038821 @default.
- W2225746578 cites W2024103415 @default.
- W2225746578 cites W2030968933 @default.
- W2225746578 cites W2035102793 @default.
- W2225746578 cites W2045189359 @default.
- W2225746578 cites W2055329593 @default.
- W2225746578 cites W2062616592 @default.
- W2225746578 cites W2067261017 @default.
- W2225746578 cites W2068672210 @default.
- W2225746578 cites W2071059977 @default.
- W2225746578 cites W2080761272 @default.
- W2225746578 cites W2084304471 @default.
- W2225746578 cites W2089363473 @default.
- W2225746578 cites W2091319838 @default.
- W2225746578 cites W2095588202 @default.
- W2225746578 cites W2124921649 @default.
- W2225746578 cites W2136300727 @default.
- W2225746578 cites W2136931384 @default.
- W2225746578 cites W2145299611 @default.
- W2225746578 cites W2163125062 @default.
- W2225746578 cites W2165749758 @default.
- W2225746578 cites W2318289524 @default.
- W2225746578 cites W2331685450 @default.
- W2225746578 cites W2411352711 @default.
- W2225746578 cites W35603984 @default.
- W2225746578 doi "https://doi.org/10.4103/0973-1296.157665" @default.
- W2225746578 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4461969" @default.
- W2225746578 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26109775" @default.
- W2225746578 hasPublicationYear "2015" @default.
- W2225746578 type Work @default.
- W2225746578 sameAs 2225746578 @default.
- W2225746578 citedByCount "29" @default.
- W2225746578 countsByYear W22257465782016 @default.
- W2225746578 countsByYear W22257465782017 @default.
- W2225746578 countsByYear W22257465782018 @default.
- W2225746578 countsByYear W22257465782019 @default.
- W2225746578 countsByYear W22257465782021 @default.
- W2225746578 countsByYear W22257465782022 @default.
- W2225746578 countsByYear W22257465782023 @default.
- W2225746578 crossrefType "journal-article" @default.
- W2225746578 hasAuthorship W2225746578A5003114465 @default.
- W2225746578 hasAuthorship W2225746578A5030284617 @default.
- W2225746578 hasAuthorship W2225746578A5068867176 @default.
- W2225746578 hasAuthorship W2225746578A5070047751 @default.
- W2225746578 hasAuthorship W2225746578A5072357794 @default.
- W2225746578 hasAuthorship W2225746578A5084171007 @default.
- W2225746578 hasBestOaLocation W22257465782 @default.
- W2225746578 hasConcept C185592680 @default.
- W2225746578 hasConcept C2776474821 @default.
- W2225746578 hasConcept C2778004101 @default.
- W2225746578 hasConcept C2779220235 @default.
- W2225746578 hasConcept C2780104969 @default.
- W2225746578 hasConcept C2781144210 @default.
- W2225746578 hasConcept C2781213060 @default.
- W2225746578 hasConcept C2781401929 @default.
- W2225746578 hasConcept C31903555 @default.
- W2225746578 hasConcept C43617362 @default.
- W2225746578 hasConcept C523546767 @default.
- W2225746578 hasConcept C54355233 @default.
- W2225746578 hasConcept C55493867 @default.
- W2225746578 hasConcept C556039675 @default.
- W2225746578 hasConcept C71924100 @default.
- W2225746578 hasConcept C86803240 @default.
- W2225746578 hasConceptScore W2225746578C185592680 @default.
- W2225746578 hasConceptScore W2225746578C2776474821 @default.
- W2225746578 hasConceptScore W2225746578C2778004101 @default.
- W2225746578 hasConceptScore W2225746578C2779220235 @default.
- W2225746578 hasConceptScore W2225746578C2780104969 @default.
- W2225746578 hasConceptScore W2225746578C2781144210 @default.
- W2225746578 hasConceptScore W2225746578C2781213060 @default.
- W2225746578 hasConceptScore W2225746578C2781401929 @default.
- W2225746578 hasConceptScore W2225746578C31903555 @default.
- W2225746578 hasConceptScore W2225746578C43617362 @default.
- W2225746578 hasConceptScore W2225746578C523546767 @default.
- W2225746578 hasConceptScore W2225746578C54355233 @default.
- W2225746578 hasConceptScore W2225746578C55493867 @default.
- W2225746578 hasConceptScore W2225746578C556039675 @default.