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- W2226810034 abstract "Drug information is necessary at all stages of drug circulation. Drug information can improve quality and safety of patient care. Error or inaccuracy in drug information sources can produce medication errors. In this context, the CNHIM as created in November 2001 a new activity infovigilance. It is a new concept for prevention of medication errors. The aim of this study has been to evaluate the impact of CNHIM infovigilance on the Summary Product Characteristics’ (SPCs) contents. For this daily activity, all SPCs are analysed before integration in Theriaque drug database (www.theriaque.org). The study was performed over a 22 months period. Each problem has been identified, integrated in an epidemiological register, and notified to AFSSAPS: 153 problems for 206 drugs have been notified to AFSSAPS. Notifications according to the type of problem were inaccuracyconfusion (24.2%), discordance between SPC rubrics (24.2%), discordance between generics SPCs (36.6%), and discordance between new SPC and old SPC (15%). 61% of the problems were assessed as with an impact on patients. 74% of the problems were corrected by CNHIM pharmacists before integration in Theriaque. Only 24% of the notifications were corrected by AFSSAPS. This study shows that the official drugs information could contain errors. Our efforts to improve the quality of drug information sources have only a moderate impact. This might be explained by long and variable updating delays from AFSSAPS. Significance of drug information in the prevention of medication errors is mentioned in multiple publications. But there is not any publication assessing the rate of potential medication errors related to drug information. The increasing number of marketed drugs makes it impossible for health practitioners to acquire all knowledge about these drugs. Consequently, the quality of information sources and the quality of integration in technological information are significant. One benefit of infovigilance was to improve the quality of the information sources. For these reasons, our activity of infovigilance has to be continued." @default.
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- W2226810034 date "2004-04-01" @default.
- W2226810034 modified "2023-09-28" @default.
- W2226810034 title "Infovigilance: impact on the summary product characteristics contents" @default.
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