FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2227285940> ?p ?o ?g. }

• W2227285940 endingPage "61" @default.
• W2227285940 startingPage "54" @default.
• W2227285940 abstract "Background and objectives The main objectives of the Randomized Intervention for Children with Vesicoureteral Reflux (RIVUR) trial were to evaluate the role of antimicrobial prophylaxis in the prevention of recurrent urinary tract infection (UTI) and renal scarring in children with vesicoureteral reflux (VUR). We present a comprehensive evaluation of renal scarring outcomes in RIVUR trial participants. Design, setting, participants, & measurements This multicenter, randomized, placebo-controlled trial enrolled 607 children aged 2–71 months with grade 1–4 VUR diagnosed after a first or second febrile or symptomatic UTI. Study participants received trimethoprim-sulfamethoxazole or placebo and were followed for 2 years. Renal scarring was evaluated by baseline and follow-up 99mtechnetium dimercaptosuccinic acid (DMSA) renal scans that were reviewed independently by two blinded reference radiologists. Results At the end of the study, 58 (10%) of 599 children and 63 (5%) of 1197 renal units had renal scarring. New renal scarring did not differ between the prophylaxis and placebo groups (6% versus 7%, respectively). Children with renal scarring were significantly older (median age, 26 versus 11 months; P=0.01), had a second UTI before enrollment (odds ratio [OR], 2.85; 95% confidence interval [95% CI], 1.38 to 5.92), were more likely to be Hispanic (OR, 2.22; 95% CI, 1.13 to 4.34), and had higher grades of VUR (OR, 2.79; 95% CI, 1.56 to 5.0). The proportion of new scars in renal units with grade 4 VUR was significantly higher than in units with no VUR (OR, 24.2; 95% CI, 6.4 to 91.2). Conclusions Significantly more renal scarring was seen in relatively older children and in those with a second episode of febrile or symptomatic UTI before randomization. Preexisting and new renal scars occurred significantly more in renal units with grade 4 VUR than in those with low-grade or no VUR. Antimicrobial prophylaxis did not decrease the risk of renal scarring." @default.
• W2227285940 created "2016-06-24" @default.
• W2227285940 creator A5005930986 @default.
• W2227285940 creator A5007870798 @default.
• W2227285940 creator A5015387097 @default.
• W2227285940 creator A5021146646 @default.
• W2227285940 creator A5024904142 @default.
• W2227285940 creator A5025478600 @default.
• W2227285940 creator A5028140982 @default.
• W2227285940 creator A5030050113 @default.
• W2227285940 creator A5048077398 @default.
• W2227285940 creator A5070797280 @default.
• W2227285940 creator A5079427944 @default.
• W2227285940 creator A5080360970 @default.
• W2227285940 date "2016-01-01" @default.
• W2227285940 modified "2023-10-01" @default.
• W2227285940 title "Renal Scarring in the Randomized Intervention for Children with Vesicoureteral Reflux (RIVUR) Trial" @default.
• W2227285940 cites W1485271732 @default.
• W2227285940 cites W1565039273 @default.
• W2227285940 cites W1977216130 @default.
• W2227285940 cites W1980397922 @default.
• W2227285940 cites W1981559796 @default.
• W2227285940 cites W1991370920 @default.
• W2227285940 cites W1993243668 @default.
• W2227285940 cites W2014638223 @default.
• W2227285940 cites W2022482132 @default.
• W2227285940 cites W2032536858 @default.
• W2227285940 cites W2033671162 @default.
• W2227285940 cites W2034884954 @default.
• W2227285940 cites W2067374681 @default.
• W2227285940 cites W2068406686 @default.
• W2227285940 cites W2070159741 @default.
• W2227285940 cites W2073206205 @default.
• W2227285940 cites W2082988422 @default.
• W2227285940 cites W2087044185 @default.
• W2227285940 cites W2087585674 @default.
• W2227285940 cites W2088703171 @default.
• W2227285940 cites W2096930444 @default.
• W2227285940 cites W2099459530 @default.
• W2227285940 cites W2104986480 @default.
• W2227285940 cites W2110484134 @default.
• W2227285940 cites W2110630072 @default.
• W2227285940 cites W2119403541 @default.
• W2227285940 cites W2121577182 @default.
• W2227285940 cites W2135707662 @default.
• W2227285940 cites W2138705120 @default.
• W2227285940 cites W2279662535 @default.
• W2227285940 cites W2299595776 @default.
• W2227285940 cites W2461477450 @default.
• W2227285940 cites W3184192997 @default.
• W2227285940 cites W4237659836 @default.
• W2227285940 doi "https://doi.org/10.2215/cjn.05210515" @default.
• W2227285940 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4702233" @default.
• W2227285940 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26555605" @default.
• W2227285940 hasPublicationYear "2016" @default.
• W2227285940 type Work @default.
• W2227285940 sameAs 2227285940 @default.
• W2227285940 citedByCount "84" @default.
• W2227285940 countsByYear W22272859402016 @default.
• W2227285940 countsByYear W22272859402017 @default.
• W2227285940 countsByYear W22272859402018 @default.
• W2227285940 countsByYear W22272859402019 @default.
• W2227285940 countsByYear W22272859402020 @default.
• W2227285940 countsByYear W22272859402021 @default.
• W2227285940 countsByYear W22272859402022 @default.
• W2227285940 countsByYear W22272859402023 @default.
• W2227285940 crossrefType "journal-article" @default.
• W2227285940 hasAuthorship W2227285940A5005930986 @default.
• W2227285940 hasAuthorship W2227285940A5007870798 @default.
• W2227285940 hasAuthorship W2227285940A5015387097 @default.
• W2227285940 hasAuthorship W2227285940A5021146646 @default.
• W2227285940 hasAuthorship W2227285940A5024904142 @default.
• W2227285940 hasAuthorship W2227285940A5025478600 @default.
• W2227285940 hasAuthorship W2227285940A5028140982 @default.
• W2227285940 hasAuthorship W2227285940A5030050113 @default.
• W2227285940 hasAuthorship W2227285940A5048077398 @default.
• W2227285940 hasAuthorship W2227285940A5070797280 @default.
• W2227285940 hasAuthorship W2227285940A5079427944 @default.
• W2227285940 hasAuthorship W2227285940A5080360970 @default.
• W2227285940 hasBestOaLocation W22272859401 @default.
• W2227285940 hasConcept C126322002 @default.
• W2227285940 hasConcept C126894567 @default.
• W2227285940 hasConcept C141071460 @default.
• W2227285940 hasConcept C142724271 @default.
• W2227285940 hasConcept C156957248 @default.
• W2227285940 hasConcept C168563851 @default.
• W2227285940 hasConcept C204787440 @default.
• W2227285940 hasConcept C27081682 @default.
• W2227285940 hasConcept C2776299442 @default.
• W2227285940 hasConcept C2777609623 @default.
• W2227285940 hasConcept C2779086996 @default.
• W2227285940 hasConcept C2779134260 @default.
• W2227285940 hasConcept C43270747 @default.
• W2227285940 hasConcept C54847362 @default.
• W2227285940 hasConcept C71924100 @default.
• W2227285940 hasConcept C77411442 @default.
• W2227285940 hasConceptScore W2227285940C126322002 @default.
• W2227285940 hasConceptScore W2227285940C126894567 @default.

• next