FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2227382309> ?p ?o ?g. }

• W2227382309 abstract "The expression of lactase which digests lactose from milk in humans is generally lost after weaning, but selected mutations influencing the promoter of the lactase gene have spread into the human populations. This is considered a classical example of gene-culture co-evolution, and several studies suggested that the lactase gene has been under strong directional evolutionary selective pressure in the past 5000 to 10,000 years. In the present study we investigated the distribution of three gene variants leading to lactase persistence in 12 different East African populations as well as one European population. Our results show that with the exception of Copts and Nilotic populations who are fully lactose non-persistent, the majority of populations of East Africa show at least partly lactose persistence, with both ethnic and socio-economic aspects playing an important role in the distribution of genetic variants. In this study, the variants C/G-13907 and T/G-13915, which are the major variants among the nomadic Arabs in the Arabia and Beja of East Africa, showed remarkable frequencies in Sudanese populations, especially those of pastoralists, in line with the historical links and bidirectional migration of nomadic populations between Arabia and East Africa. The C/T-13910 variant, generally associated with European populations is uniquely present among the Fulani. These data indicate that a combination of socio-economic, ethnic and evolutionary factors converged to shape the genetic structure of lactase persistence in East African populations." @default.
• W2227382309 created "2016-06-24" @default.
• W2227382309 creator A5019352309 @default.
• W2227382309 creator A5027955775 @default.
• W2227382309 creator A5036752858 @default.
• W2227382309 creator A5042769516 @default.
• W2227382309 creator A5055966388 @default.
• W2227382309 creator A5056218109 @default.
• W2227382309 creator A5089769587 @default.
• W2227382309 date "2016-01-04" @default.
• W2227382309 modified "2023-10-12" @default.
• W2227382309 title "Genetic diversity of lactase persistence in East African populations" @default.
• W2227382309 cites W1594379861 @default.
• W2227382309 cites W1965218239 @default.
• W2227382309 cites W1972327726 @default.
• W2227382309 cites W1976649490 @default.
• W2227382309 cites W2000380175 @default.
• W2227382309 cites W2001722477 @default.
• W2227382309 cites W2029160566 @default.
• W2227382309 cites W2031103971 @default.
• W2227382309 cites W2046945797 @default.
• W2227382309 cites W2057918014 @default.
• W2227382309 cites W2078329360 @default.
• W2227382309 cites W2094614504 @default.
• W2227382309 cites W2100093862 @default.
• W2227382309 cites W2114883793 @default.
• W2227382309 cites W2120831613 @default.
• W2227382309 cites W2121146210 @default.
• W2227382309 cites W2127249061 @default.
• W2227382309 cites W2136627601 @default.
• W2227382309 cites W2154403877 @default.
• W2227382309 cites W2156918287 @default.
• W2227382309 cites W2169421412 @default.
• W2227382309 cites W4239149238 @default.
• W2227382309 cites W4248161719 @default.
• W2227382309 cites W604859579 @default.
• W2227382309 doi "https://doi.org/10.1186/s13104-015-1833-1" @default.
• W2227382309 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4700599" @default.
• W2227382309 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26728963" @default.
• W2227382309 hasPublicationYear "2016" @default.
• W2227382309 type Work @default.
• W2227382309 sameAs 2227382309 @default.
• W2227382309 citedByCount "19" @default.
• W2227382309 countsByYear W22273823092016 @default.
• W2227382309 countsByYear W22273823092017 @default.
• W2227382309 countsByYear W22273823092018 @default.
• W2227382309 countsByYear W22273823092020 @default.
• W2227382309 countsByYear W22273823092021 @default.
• W2227382309 countsByYear W22273823092023 @default.
• W2227382309 crossrefType "journal-article" @default.
• W2227382309 hasAuthorship W2227382309A5019352309 @default.
• W2227382309 hasAuthorship W2227382309A5027955775 @default.
• W2227382309 hasAuthorship W2227382309A5036752858 @default.
• W2227382309 hasAuthorship W2227382309A5042769516 @default.
• W2227382309 hasAuthorship W2227382309A5055966388 @default.
• W2227382309 hasAuthorship W2227382309A5056218109 @default.
• W2227382309 hasAuthorship W2227382309A5089769587 @default.
• W2227382309 hasBestOaLocation W22273823091 @default.
• W2227382309 hasConcept C127413603 @default.
• W2227382309 hasConcept C144024400 @default.
• W2227382309 hasConcept C149923435 @default.
• W2227382309 hasConcept C187320778 @default.
• W2227382309 hasConcept C2777432071 @default.
• W2227382309 hasConcept C2778724459 @default.
• W2227382309 hasConcept C2778974006 @default.
• W2227382309 hasConcept C2781009140 @default.
• W2227382309 hasConcept C2908647359 @default.
• W2227382309 hasConcept C54355233 @default.
• W2227382309 hasConcept C55493867 @default.
• W2227382309 hasConcept C78458016 @default.
• W2227382309 hasConcept C81977670 @default.
• W2227382309 hasConcept C86803240 @default.
• W2227382309 hasConcept C90856448 @default.
• W2227382309 hasConceptScore W2227382309C127413603 @default.
• W2227382309 hasConceptScore W2227382309C144024400 @default.
• W2227382309 hasConceptScore W2227382309C149923435 @default.
• W2227382309 hasConceptScore W2227382309C187320778 @default.
• W2227382309 hasConceptScore W2227382309C2777432071 @default.
• W2227382309 hasConceptScore W2227382309C2778724459 @default.
• W2227382309 hasConceptScore W2227382309C2778974006 @default.
• W2227382309 hasConceptScore W2227382309C2781009140 @default.
• W2227382309 hasConceptScore W2227382309C2908647359 @default.
• W2227382309 hasConceptScore W2227382309C54355233 @default.
• W2227382309 hasConceptScore W2227382309C55493867 @default.
• W2227382309 hasConceptScore W2227382309C78458016 @default.
• W2227382309 hasConceptScore W2227382309C81977670 @default.
• W2227382309 hasConceptScore W2227382309C86803240 @default.
• W2227382309 hasConceptScore W2227382309C90856448 @default.
• W2227382309 hasFunder F4320334678 @default.
• W2227382309 hasIssue "1" @default.
• W2227382309 hasLocation W22273823091 @default.
• W2227382309 hasLocation W22273823092 @default.
• W2227382309 hasLocation W22273823093 @default.
• W2227382309 hasLocation W22273823094 @default.
• W2227382309 hasLocation W22273823095 @default.
• W2227382309 hasOpenAccess W2227382309 @default.
• W2227382309 hasPrimaryLocation W22273823091 @default.
• W2227382309 hasRelatedWork W198588116 @default.
• W2227382309 hasRelatedWork W2090745996 @default.
• W2227382309 hasRelatedWork W2183327365 @default.

• next