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- W2227544048 abstract "OBJECTIVE:To describe a clinical case that highlights a rare aspect of language localization in the brain. The case involves a right-handed man with a left hemiplegia and aphasia due to a right middle cerebral artery infarction affecting the subcortical territory.BACKGROUND: Aphasia is a loss of ability to understand or express language caused by injury to the brain. In right-handed individuals, language localizes to the left hemisphere, although in up to 7[percnt] of right-handers language is right lateralized.DESIGN/METHODS: We describe the clinical history and imaging findings in a right-handed man with aphasia and left hemiplegia due to damage of subcortical structures in the right hemisphere.RESULTS:A 50-year-old right handed man with history of hypertension and diabetes mellitus presented with progressive left hemiplegia and global aphasia. He was brought to the Emergency department about 10 hours after symptom onset. In the emergency department his blood pressure was 184/112 and heart rate 91. His NIH stroke scale was 10 for consciousness (2), left facial droop (2), and speech (3), left upper extremity weakness (3) and left lower extremity weakness. On exam, he was anarthric. An MRI showed a right subcortical frontal stroke. He was started on aspirin 81 mg daily, clopidogrel 75 mg daily and atorvastatin 80 mg daily for secondary stroke prevention. On hospital day 3, he was able to say one word and follow simple commands. On hospital day 7, he was discharged to a rehabilitation facility.CONCLUSIONS: This patient is a rare case in which right-sided subcortical damage results in aphasia. The most comprehensive evidence on language lateralization comes from functional studies of healthy adults that differ in their degree of handedness. It appears that the degree of right-handedness correlates, with the degree of left hemisphere language dominance. Disclosure: Dr. Murray has nothing to disclose. Dr. Kase has nothing to disclose. Dr. Nguyen has nothing to disclose. Dr. Bickart has nothing to disclose." @default.
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- W2227544048 date "2015-04-06" @default.
- W2227544048 modified "2023-09-30" @default.
- W2227544048 title "Crossed Subcortical Aphasia (P1.048)" @default.
- W2227544048 hasPublicationYear "2015" @default.
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