Matches in SemOpenAlex for { <https://semopenalex.org/work/W2227690332> ?p ?o ?g. }
Showing items 1 to 84 of
84
with 100 items per page.
- W2227690332 endingPage "37" @default.
- W2227690332 startingPage "129" @default.
- W2227690332 abstract "To explore the relative species specificities of the IgE and IgG antibody responses to helminth infections in man, we studied four pools of sera from patients infected with Wuchereria bancrofti, Brugia malayi, Onchocerca volvulus or Ascaris lumbricoides and ten individual sera from patients with onchocerciasis. IgE antibodies were detected by radioallergosorbent test (RAST) analysis and IgG antibodies by a Staphylococcus protein A radioimmunoassay (Staph A-RIA). Analysis of the binding curves with four different immunosorbents (prepared from antigens of B. malayi, O. volvulus, Dipetalonema viteae and A. lumbricoides) in the RAST and the binding curves with these same four antigens in the Staph A-RIA confirmed the relative species specificities for both the IgE and IgG antibody responses. Then determination of these antibody levels after specific absorption of the sera with both homologous and heterologous antigens showed that in all instances there was significantly less cross-reactivity with heterologous parasite antigens (i.e. higher species specificity) in the IgE antibody response to filarial infection than in the corresponding IgG antibody response. Such findings imply that efforts toward developing techniques for specific immunodiagnosis of filarial infections are likely to be particularly successful if focused on the IgE antibody response of exposed individuals." @default.
- W2227690332 created "2016-06-24" @default.
- W2227690332 creator A5002771486 @default.
- W2227690332 creator A5035405210 @default.
- W2227690332 creator A5047246603 @default.
- W2227690332 date "1982-01-01" @default.
- W2227690332 modified "2023-09-26" @default.
- W2227690332 title "IgE antibodies are more species-specific than IgG antibodies in human onchocerciasis and lymphatic filariasis." @default.
- W2227690332 cites W1416372546 @default.
- W2227690332 cites W1482718420 @default.
- W2227690332 cites W1588885776 @default.
- W2227690332 cites W1893651774 @default.
- W2227690332 cites W1963998251 @default.
- W2227690332 cites W1969536848 @default.
- W2227690332 cites W2001489640 @default.
- W2227690332 cites W2028471176 @default.
- W2227690332 cites W2031940078 @default.
- W2227690332 cites W2073051680 @default.
- W2227690332 cites W2073519401 @default.
- W2227690332 cites W2164849709 @default.
- W2227690332 cites W2263903243 @default.
- W2227690332 cites W2397724541 @default.
- W2227690332 cites W2400849558 @default.
- W2227690332 cites W2419557556 @default.
- W2227690332 cites W2427974379 @default.
- W2227690332 cites W2618298765 @default.
- W2227690332 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1555146" @default.
- W2227690332 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7199027" @default.
- W2227690332 hasPublicationYear "1982" @default.
- W2227690332 type Work @default.
- W2227690332 sameAs 2227690332 @default.
- W2227690332 citedByCount "21" @default.
- W2227690332 countsByYear W22276903322022 @default.
- W2227690332 crossrefType "journal-article" @default.
- W2227690332 hasAuthorship W2227690332A5002771486 @default.
- W2227690332 hasAuthorship W2227690332A5035405210 @default.
- W2227690332 hasAuthorship W2227690332A5047246603 @default.
- W2227690332 hasConcept C141105273 @default.
- W2227690332 hasConcept C147483822 @default.
- W2227690332 hasConcept C159654299 @default.
- W2227690332 hasConcept C165901193 @default.
- W2227690332 hasConcept C203014093 @default.
- W2227690332 hasConcept C2775848585 @default.
- W2227690332 hasConcept C2777364306 @default.
- W2227690332 hasConcept C2777629521 @default.
- W2227690332 hasConcept C2778672586 @default.
- W2227690332 hasConcept C2779027325 @default.
- W2227690332 hasConcept C2780727990 @default.
- W2227690332 hasConcept C2780898057 @default.
- W2227690332 hasConcept C86803240 @default.
- W2227690332 hasConceptScore W2227690332C141105273 @default.
- W2227690332 hasConceptScore W2227690332C147483822 @default.
- W2227690332 hasConceptScore W2227690332C159654299 @default.
- W2227690332 hasConceptScore W2227690332C165901193 @default.
- W2227690332 hasConceptScore W2227690332C203014093 @default.
- W2227690332 hasConceptScore W2227690332C2775848585 @default.
- W2227690332 hasConceptScore W2227690332C2777364306 @default.
- W2227690332 hasConceptScore W2227690332C2777629521 @default.
- W2227690332 hasConceptScore W2227690332C2778672586 @default.
- W2227690332 hasConceptScore W2227690332C2779027325 @default.
- W2227690332 hasConceptScore W2227690332C2780727990 @default.
- W2227690332 hasConceptScore W2227690332C2780898057 @default.
- W2227690332 hasConceptScore W2227690332C86803240 @default.
- W2227690332 hasIssue "1" @default.
- W2227690332 hasLocation W22276903321 @default.
- W2227690332 hasOpenAccess W2227690332 @default.
- W2227690332 hasPrimaryLocation W22276903321 @default.
- W2227690332 hasRelatedWork W1978292025 @default.
- W2227690332 hasRelatedWork W19856627 @default.
- W2227690332 hasRelatedWork W2054516584 @default.
- W2227690332 hasRelatedWork W2114624351 @default.
- W2227690332 hasRelatedWork W2124562194 @default.
- W2227690332 hasRelatedWork W2164849709 @default.
- W2227690332 hasRelatedWork W2227690332 @default.
- W2227690332 hasRelatedWork W2413406773 @default.
- W2227690332 hasRelatedWork W2922488180 @default.
- W2227690332 hasRelatedWork W313037278 @default.
- W2227690332 hasVolume "45" @default.
- W2227690332 isParatext "false" @default.
- W2227690332 isRetracted "false" @default.
- W2227690332 magId "2227690332" @default.
- W2227690332 workType "article" @default.