FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2227700557> ?p ?o ?g. }

• W2227700557 endingPage "e0146174" @default.
• W2227700557 startingPage "e0146174" @default.
• W2227700557 abstract "The G-quadruplex is a non-canonical DNA structure biologically significant in DNA replication, transcription and telomere stability. To date, only G4s with all guanines originating from the same strand of DNA have been considered in the context of the human nuclear genome. Here, I discuss interstrand topological configurations of G-quadruplex DNA, consisting of guanines from both strands of genomic DNA; an algorithm is presented for predicting such structures. I have identified over 550,000 non-overlapping interstrand G-quadruplex forming sequences in the human genome--significantly more than intrastrand configurations. Functional analysis of interstrand G-quadruplex sites shows strong association with transcription initiation, the results are consistent with the XPB and XPD transcriptional helicases binding only to G-quadruplex DNA with interstrand topology. Interstrand quadruplexes are also enriched in origin of replication sites. Several topology classes of interstrand quadruplex-forming sequences are possible, and different topologies are enriched in different types of structural elements. The list of interstrand quadruplex forming sequences, and the computer program used for their prediction are available at the web address http://moment.utmb.edu/allquads." @default.
• W2227700557 created "2016-06-24" @default.
• W2227700557 creator A5077283778 @default.
• W2227700557 date "2016-01-04" @default.
• W2227700557 modified "2023-10-14" @default.
• W2227700557 title "G-Quadruplexes Involving Both Strands of Genomic DNA Are Highly Abundant and Colocalize with Functional Sites in the Human Genome" @default.
• W2227700557 cites W1450574606 @default.
• W2227700557 cites W1914649288 @default.
• W2227700557 cites W1977305809 @default.
• W2227700557 cites W1990635146 @default.
• W2227700557 cites W2002566486 @default.
• W2227700557 cites W2007634776 @default.
• W2227700557 cites W2011990150 @default.
• W2227700557 cites W2013356258 @default.
• W2227700557 cites W2021191052 @default.
• W2227700557 cites W2027696068 @default.
• W2227700557 cites W2039857324 @default.
• W2227700557 cites W2060356703 @default.
• W2227700557 cites W2063894264 @default.
• W2227700557 cites W2073722866 @default.
• W2227700557 cites W2074139680 @default.
• W2227700557 cites W2075470292 @default.
• W2227700557 cites W2077605689 @default.
• W2227700557 cites W2078491086 @default.
• W2227700557 cites W2080142197 @default.
• W2227700557 cites W2083173639 @default.
• W2227700557 cites W2083703501 @default.
• W2227700557 cites W2086499080 @default.
• W2227700557 cites W2088462767 @default.
• W2227700557 cites W2097372529 @default.
• W2227700557 cites W2099929096 @default.
• W2227700557 cites W2102619694 @default.
• W2227700557 cites W2105669930 @default.
• W2227700557 cites W2119449687 @default.
• W2227700557 cites W2119762097 @default.
• W2227700557 cites W2121481176 @default.
• W2227700557 cites W2122846880 @default.
• W2227700557 cites W2125116394 @default.
• W2227700557 cites W2141507075 @default.
• W2227700557 cites W2147643191 @default.
• W2227700557 cites W2148660588 @default.
• W2227700557 cites W2153879694 @default.
• W2227700557 cites W2156056868 @default.
• W2227700557 cites W2156206373 @default.
• W2227700557 cites W2164627013 @default.
• W2227700557 cites W2164740045 @default.
• W2227700557 cites W2169745877 @default.
• W2227700557 cites W2170754011 @default.
• W2227700557 cites W2171830519 @default.
• W2227700557 cites W2171928459 @default.
• W2227700557 cites W2331682169 @default.
• W2227700557 doi "https://doi.org/10.1371/journal.pone.0146174" @default.
• W2227700557 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4699641" @default.
• W2227700557 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26727593" @default.
• W2227700557 hasPublicationYear "2016" @default.
• W2227700557 type Work @default.
• W2227700557 sameAs 2227700557 @default.
• W2227700557 citedByCount "43" @default.
• W2227700557 countsByYear W22277005572016 @default.
• W2227700557 countsByYear W22277005572017 @default.
• W2227700557 countsByYear W22277005572018 @default.
• W2227700557 countsByYear W22277005572019 @default.
• W2227700557 countsByYear W22277005572020 @default.
• W2227700557 countsByYear W22277005572021 @default.
• W2227700557 countsByYear W22277005572022 @default.
• W2227700557 countsByYear W22277005572023 @default.
• W2227700557 crossrefType "journal-article" @default.
• W2227700557 hasAuthorship W2227700557A5077283778 @default.
• W2227700557 hasBestOaLocation W22277005571 @default.
• W2227700557 hasConcept C104317684 @default.
• W2227700557 hasConcept C138885662 @default.
• W2227700557 hasConcept C141231307 @default.
• W2227700557 hasConcept C177336024 @default.
• W2227700557 hasConcept C179926584 @default.
• W2227700557 hasConcept C197077220 @default.
• W2227700557 hasConcept C41895202 @default.
• W2227700557 hasConcept C54355233 @default.
• W2227700557 hasConcept C552990157 @default.
• W2227700557 hasConcept C70721500 @default.
• W2227700557 hasConcept C73573662 @default.
• W2227700557 hasConcept C83762044 @default.
• W2227700557 hasConcept C86803240 @default.
• W2227700557 hasConceptScore W2227700557C104317684 @default.
• W2227700557 hasConceptScore W2227700557C138885662 @default.
• W2227700557 hasConceptScore W2227700557C141231307 @default.
• W2227700557 hasConceptScore W2227700557C177336024 @default.
• W2227700557 hasConceptScore W2227700557C179926584 @default.
• W2227700557 hasConceptScore W2227700557C197077220 @default.
• W2227700557 hasConceptScore W2227700557C41895202 @default.
• W2227700557 hasConceptScore W2227700557C54355233 @default.
• W2227700557 hasConceptScore W2227700557C552990157 @default.
• W2227700557 hasConceptScore W2227700557C70721500 @default.
• W2227700557 hasConceptScore W2227700557C73573662 @default.
• W2227700557 hasConceptScore W2227700557C83762044 @default.
• W2227700557 hasConceptScore W2227700557C86803240 @default.
• W2227700557 hasIssue "1" @default.
• W2227700557 hasLocation W22277005571 @default.
• W2227700557 hasLocation W22277005572 @default.

• next