FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2227776938> ?p ?o ?g. }

• W2227776938 endingPage "376" @default.
• W2227776938 startingPage "371" @default.
• W2227776938 abstract "Intervertebral disk degeneration (IDD) is strongly associated with genetic predisposition and environmental susceptibility. Several studies been conducted to investigate the potential association between IDD and FokI polymorphism located in the gene encoding the vitamin D receptor (VDR), and inconsistent conclusions had been reached among different ethnic populations. In order to assess the association between the FokI polymorphism and the risk of IDD, we performed a comprehensive and systematic meta-analysis. Candidate articles were retrieved from PubMed, EMBASE, China National Knowledge Infrastructure (CNKI), and China Biology Medical (CBM) with strict inclusion criteria in January 2015. Among the 54 articles that were retrieved, only eight studies met the inclusion criteria. The pooled data analysis based on allele contrast, homozygote, heterozygote, dominant, and recessive models revealed no significant correlation between the FokI polymorphism and the risk of IDD. However, when stratified by ethnicity, significant associations were detected for Hispanics based on allele contrast (OR = 1.395, 95% CI = 1.059–1.836, P = 0.018), homozygote (OR = 1.849, 95% CI = 1.001–3.416, P = 0.049), heterozygote (OR = 1.254, 95% CI = 1.049–1.498, P = 0.013), and dominant (OR = 1.742, 95% CI = 1.174–2.583, P = 0.006) models, and for Asians using the dominant model (OR = 1.293, 95% CI = 1.025–1.632, P = 0.030), whereas there is no significant association detected for Caucasians. In conclusion, FokI polymorphism is not generally associated with IDD, but there is increased risk for IDD in Hispanics and Asians carrying FokI allele T." @default.
• W2227776938 created "2016-06-24" @default.
• W2227776938 creator A5039213269 @default.
• W2227776938 creator A5044549205 @default.
• W2227776938 creator A5066725248 @default.
• W2227776938 creator A5080477696 @default.
• W2227776938 creator A5086414305 @default.
• W2227776938 date "2015-12-01" @default.
• W2227776938 modified "2023-09-30" @default.
• W2227776938 title "Association Between VDR FokI Polymorphism and Intervertebral Disk Degeneration" @default.
• W2227776938 cites W1582290662 @default.
• W2227776938 cites W1964651930 @default.
• W2227776938 cites W1965414667 @default.
• W2227776938 cites W1970987419 @default.
• W2227776938 cites W1976532153 @default.
• W2227776938 cites W1976713808 @default.
• W2227776938 cites W199619328 @default.
• W2227776938 cites W1996563157 @default.
• W2227776938 cites W1996685480 @default.
• W2227776938 cites W1998901574 @default.
• W2227776938 cites W2005936777 @default.
• W2227776938 cites W2009609051 @default.
• W2227776938 cites W2039948014 @default.
• W2227776938 cites W2046310455 @default.
• W2227776938 cites W2047681882 @default.
• W2227776938 cites W2049584813 @default.
• W2227776938 cites W2050907928 @default.
• W2227776938 cites W2067995312 @default.
• W2227776938 cites W2068591086 @default.
• W2227776938 cites W2077425856 @default.
• W2227776938 cites W2082568701 @default.
• W2227776938 cites W2099691945 @default.
• W2227776938 cites W2099946862 @default.
• W2227776938 cites W2120241921 @default.
• W2227776938 cites W2149587761 @default.
• W2227776938 cites W2162733084 @default.
• W2227776938 cites W7041188 @default.
• W2227776938 doi "https://doi.org/10.1016/j.gpb.2015.11.003" @default.
• W2227776938 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4747649" @default.
• W2227776938 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26772150" @default.
• W2227776938 hasPublicationYear "2015" @default.
• W2227776938 type Work @default.
• W2227776938 sameAs 2227776938 @default.
• W2227776938 citedByCount "18" @default.
• W2227776938 countsByYear W22277769382016 @default.
• W2227776938 countsByYear W22277769382017 @default.
• W2227776938 countsByYear W22277769382018 @default.
• W2227776938 countsByYear W22277769382019 @default.
• W2227776938 countsByYear W22277769382020 @default.
• W2227776938 countsByYear W22277769382021 @default.
• W2227776938 countsByYear W22277769382022 @default.
• W2227776938 countsByYear W22277769382023 @default.
• W2227776938 crossrefType "journal-article" @default.
• W2227776938 hasAuthorship W2227776938A5039213269 @default.
• W2227776938 hasAuthorship W2227776938A5044549205 @default.
• W2227776938 hasAuthorship W2227776938A5066725248 @default.
• W2227776938 hasAuthorship W2227776938A5080477696 @default.
• W2227776938 hasAuthorship W2227776938A5086414305 @default.
• W2227776938 hasBestOaLocation W22277769381 @default.
• W2227776938 hasConcept C104317684 @default.
• W2227776938 hasConcept C124490489 @default.
• W2227776938 hasConcept C126322002 @default.
• W2227776938 hasConcept C149737253 @default.
• W2227776938 hasConcept C153471976 @default.
• W2227776938 hasConcept C179639408 @default.
• W2227776938 hasConcept C180754005 @default.
• W2227776938 hasConcept C2781308329 @default.
• W2227776938 hasConcept C2992519594 @default.
• W2227776938 hasConcept C54355233 @default.
• W2227776938 hasConcept C71924100 @default.
• W2227776938 hasConcept C76252995 @default.
• W2227776938 hasConcept C86803240 @default.
• W2227776938 hasConcept C90924648 @default.
• W2227776938 hasConcept C95190672 @default.
• W2227776938 hasConceptScore W2227776938C104317684 @default.
• W2227776938 hasConceptScore W2227776938C124490489 @default.
• W2227776938 hasConceptScore W2227776938C126322002 @default.
• W2227776938 hasConceptScore W2227776938C149737253 @default.
• W2227776938 hasConceptScore W2227776938C153471976 @default.
• W2227776938 hasConceptScore W2227776938C179639408 @default.
• W2227776938 hasConceptScore W2227776938C180754005 @default.
• W2227776938 hasConceptScore W2227776938C2781308329 @default.
• W2227776938 hasConceptScore W2227776938C2992519594 @default.
• W2227776938 hasConceptScore W2227776938C54355233 @default.
• W2227776938 hasConceptScore W2227776938C71924100 @default.
• W2227776938 hasConceptScore W2227776938C76252995 @default.
• W2227776938 hasConceptScore W2227776938C86803240 @default.
• W2227776938 hasConceptScore W2227776938C90924648 @default.
• W2227776938 hasConceptScore W2227776938C95190672 @default.
• W2227776938 hasIssue "6" @default.
• W2227776938 hasLocation W22277769381 @default.
• W2227776938 hasLocation W22277769382 @default.
• W2227776938 hasLocation W22277769383 @default.
• W2227776938 hasLocation W22277769384 @default.
• W2227776938 hasOpenAccess W2227776938 @default.
• W2227776938 hasPrimaryLocation W22277769381 @default.
• W2227776938 hasRelatedWork W2227776938 @default.
• W2227776938 hasRelatedWork W2412913158 @default.

• next