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- W2227886366 abstract "1. The oxygen consumption rate of near-term pups of the dogfish, Squalus suckleyi, was determined at regular intervals during the course of repeated injections of physiological saline solution, thyroid hormones, or of anti-thyroid substances. Up to 10 injections were given on alternate days.2. Of the compounds tested, triiodothyroacetic acid at a dosage level of 10 micrograms per injection was the most consistent in raising the level of oxygen consumption. The effect, however, was transitory with oxygen consumption rising to a maximum (17% to 33%) level above the saline-injected controls after four injections, thereafter declining slowly to control levels.3. L-thyroxine at a dosage level of 10 micrograms had a variable effect on oxygen consumption. In two of four experiments the oxygen consumption rate rose irregularly, reaching a level about 20% above the controls after 9-10 injections. In the remaining experiments, there was no clear tendency to remain above the controls.4. Propylthiouracil, after 9 injections, had no consistent effect on metabolic rate in four experiments.5. The results are discussed with reference to the possible level of thyroid function in these animals." @default.
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- W2227886366 date "1960-08-01" @default.
- W2227886366 modified "2023-09-24" @default.
- W2227886366 title "THYROID HORMONE TREATMENT AND OXYGEN CONSUMPTION IN EMBRYOS OF THE SPINY DOGFISH" @default.
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- W2227886366 doi "https://doi.org/10.2307/1538939" @default.
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